When the recombination process of a heavy-chain V region is complete, the heavy- and light-chain loci contain anexon that encodes the entire variable region. Which gene segment encodes the first two hypervariable regions andB strands A-F?VH or VLJH or JLDH or DLVH or JH

Answered: When the recombination process of a…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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When the recombination process of a heavy-chain V region is complete, the heavy- and light-chain loci contain an
exon that encodes the entire variable region. Which gene segment encodes the first two hypervariable regions and
B strands A-F?
VH or VL
JH or JL
DH or DL
VH or JH

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Step 1: Introduction:

Immunoglobulins, also known as antibodies, are essential for the adaptive immune system. They bind to foreign antigens, such as viruses and bacteria, and help to neutralize them. Immunoglobulin genes are organized in a unique way, with the variable region encoded by multiple gene segments that are rearranged during B cell development. This process of gene rearrangement results in a vast diversity of antibody molecules, each with a unique specificity for a particular antigen.

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