The data below are from a DNAse-Seq experiment of chromosome 22. DNAse-seq is another method for measuring chromatin organization. In the experiment, regions of chromatin are digested with DNAse I and DNA is sequenced to determined to identify cleavage sites. See this short article for complete explanation. Which of the following statements are true based on the data below (select all that apply)? A. Region C appears to be an actively transcribed region in all tissue types except trophoblasts B. Region A could be an origin of replication for the chromosome C. Region B is highly associated with nucleosomes in BE2C and Natural KIller Cells D. The genes in the fetal kidney tissue are the least actively transcribed on chromosome 22. E. The data for each tissue must be from separate people to have such a variation in DNAse sensitivity
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
The data below are from a DNAse-Seq experiment of chromosome 22. DNAse-seq is another method for measuring chromatin organization. In the experiment, regions of chromatin are digested with DNAse I and DNA is sequenced to determined to identify cleavage sites. See this short article for complete explanation. Which of the following statements are true based on the data below (select all that apply)?
| A. |
Region C appears to be an actively transcribed region in all tissue types except trophoblasts |
|
| B. |
Region A could be an origin of replication for the chromosome |
|
| C. |
Region B is highly associated with nucleosomes in BE2C and Natural KIller Cells |
|
| D. |
The genes in the fetal kidney tissue are the least actively transcribed on chromosome 22. |
|
| E. |
The data for each tissue must be from separate people to have such a variation in DNAse sensitivity |
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