We seem to know more about the structure of eukaryotic chromosomal DNA than bacterial DNA. Discuss why you think this is so,and list several experimental procedures that have yielded important information concerning the compaction of eukaryoticchromatin
Bacterial Genomics
The study of the morphological, physiological, and evolutionary aspects of the bacterial genome is referred to as bacterial genomics. This subdisciplinary field aids in understanding how genes are assembled into genomes. Further, bacterial or microbial genomics has helped researchers in understanding the pathogenicity of bacteria and other microbes.
Transformation Experiment in Bacteria
In the discovery of genetic material, the experiment conducted by Frederick Griffith on Streptococcus pneumonia proved to be a stepping stone.
Plasmids and Vectors
The DNA molecule that exists in a circular shape and is smaller in size which is capable of its replication is called Plasmids. In other words, it is called extra-chromosomal plasmid DNA. Vectors are the molecule which is capable of carrying genetic material which can be transferred into another cell and further carry out replication and expression. Plasmids can act as vectors.
We seem to know more about the structure of eukaryotic chromosomal DNA than bacterial DNA. Discuss why you think this is so,
and list several experimental procedures that have yielded important information concerning the compaction of eukaryotic
chromatin
Deoxy ribonucleic acid (DNA) is the genetic material of most organisms that carry coded genetic information in the form of nucleotide sequences. These sequences are essential for translation of proteins and they are passed to succeeding generations through successive reproduction.
The following are the main reasons due to which more information is known about the structure of the eukaryotic chromosomal DNA than bacterial DNA.
- The method of isolation of bacterial chromosomal DNA is more difficult than eukaryotic DNA.
- The size difference between the bacterial chromosomal DNA and eukaryotic chromosomal DNA.
- Irregular biochemical composition of bacterial chromosome.
- Eukaryotic chromosome has repetitive nucleosome structure, which helps in easy method of comprehension of the molecular structures of the eukaryotic chromosomal DNA.
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