3) The "Met" receptor is a membrane receptor protein responsible for initiating signal transduction pathways that cause cells to divide, among other things. After the Met receptor has been stimulated by its specific growth factor, another protein called c- Cbl will bind to the Met receptor. C-Cbl will then attach a chain of small proteins called ubiquitin to the Met receptor. These chains of ubiquitin help the cell recognize that the Met receptor should undergo receptor-mediated endocytosis, which eventually leads to the destruction of the Met receptor. Circle any answer or answers that include mutations that could cause the cell to potentially become a cancer cell. A) a mutation causing there to be too much ubiquitin protein produced. B) a mutation causing c-Cbl to be inactivated. C) a mutation causing ubiquitin to be inactivated. D) a mutation causing there to be too few Met receptors produced. E) a mutation causing the Met receptor to no longer be able to bind to its growth factor.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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3) The “Met" receptor is a membrane receptor protein responsible for initiating signal
transduction pathways that cause cells to divide, among other things.
After the Met receptor has been stimulated by its specific growth factor, another protein called c-
Cbl will bind to the Met receptor. C-Cbl will then attach a chain of small proteins called ubiquitin
to the Met receptor. These chains of ubiquitin help the cell recognize that the Met receptor should
undergo receptor-mediated endocytosis, which eventually leads to the destruction of the Met
receptor.
Circle any answer or answers that include mutations that could cause the cell to potentially
become a cancer cell.
A) a mutation causing there to be too much ubiquitin protein produced.
B) a mutation causing c-Cbl to be inactivated.
C) a mutation causing ubiquitin to be inactivated.
D) a mutation causing there to be too few Met receptors produced.
E) a mutation causing the Met receptor to no longer be able to bind to its growth factor.
NIH
nsogilam o lenog owi omi borasta od
bris nginad oinogola
oton to 1olvedsd odt no boaed uom nln bne nginod nsowad
emnbbueaOL
Transcribed Image Text:3) The “Met" receptor is a membrane receptor protein responsible for initiating signal transduction pathways that cause cells to divide, among other things. After the Met receptor has been stimulated by its specific growth factor, another protein called c- Cbl will bind to the Met receptor. C-Cbl will then attach a chain of small proteins called ubiquitin to the Met receptor. These chains of ubiquitin help the cell recognize that the Met receptor should undergo receptor-mediated endocytosis, which eventually leads to the destruction of the Met receptor. Circle any answer or answers that include mutations that could cause the cell to potentially become a cancer cell. A) a mutation causing there to be too much ubiquitin protein produced. B) a mutation causing c-Cbl to be inactivated. C) a mutation causing ubiquitin to be inactivated. D) a mutation causing there to be too few Met receptors produced. E) a mutation causing the Met receptor to no longer be able to bind to its growth factor. NIH nsogilam o lenog owi omi borasta od bris nginad oinogola oton to 1olvedsd odt no boaed uom nln bne nginod nsowad emnbbueaOL
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