The figure below illustrates a model of a signal transduction cascade, initiated by the bind- ing of a ligand to a membrane-bound receptor. ligand A partial model of a signal transduction pathway. A B inactivated molecules C D receptor protein A Based on the figure, which of the following describes the most likely outcome of a mutation that changes the intracellular region of receptor protein A? activated molecule 1 activated molecule 2 activated molecule 3 The receptor will not activate molecule 1, but the activation of molecules 2 and 3 will continue at lower rates. Molecule 1 will not become activated, preventing the activation of molecules 2 and 3 and the subsequent cellular response. The ligand will not be able to bind the membrane-bound receptor, preventing the signal transduction pathway from initiating The ligand that binds to protein A will not enter the cell, preventing the cellular response from occurring.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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The
figure below illustrates a model of a signal transduction cascade, initiated by the bind-
ing of a ligand to a membrane-bound receptor.
ligand
A partial model of a signal transduction pathway
A
inactivated
molecules
B
-receptor protein A
D
activated
molecule 1
Based on the figure, which of the following describes the most likely outcome of a mutation that changes the
intracellular region of receptor protein A?
activated
molecule 2
activated
molecule 3
The receptor will not activate molecule 1, but the activation of molecules 2 and 3 will
continue at lower rates.
Molecule 1 will not become activated, preventing the activation of molecules 2 and 3
and the subsequent cellular response.
с
The ligand will not be able to bind the membrane-bound receptor, preventing the signal
transduction pathway from initiating.
The ligand that binds to protein A will not enter the cell, preventing the cellular response
from occurring.
Transcribed Image Text:The figure below illustrates a model of a signal transduction cascade, initiated by the bind- ing of a ligand to a membrane-bound receptor. ligand A partial model of a signal transduction pathway A inactivated molecules B -receptor protein A D activated molecule 1 Based on the figure, which of the following describes the most likely outcome of a mutation that changes the intracellular region of receptor protein A? activated molecule 2 activated molecule 3 The receptor will not activate molecule 1, but the activation of molecules 2 and 3 will continue at lower rates. Molecule 1 will not become activated, preventing the activation of molecules 2 and 3 and the subsequent cellular response. с The ligand will not be able to bind the membrane-bound receptor, preventing the signal transduction pathway from initiating. The ligand that binds to protein A will not enter the cell, preventing the cellular response from occurring.
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