13. Draw the structure of the amino acid lysine showing the correct protonation states of its acid and base functional groups in a solution of lysine at pH 10.5. What is the net overall charge on lys at this pH? 14. Draw the structure of the amino acid lysine showing the correct protonation states of its acid and base functional groups in a solution of lysine at pH 8.5. What is the net overall charge on lys at this pH? ➜ Practice other questions like sample questions 12-14 using the 20 amino acids at varying pHs!!! (eg. "Draw the structure of the amino acid Histidine showing the correct protonation states of its acid and base functional groups in a solution of his at pH 5. What is the net overall charge on his at this pH?" etc...)

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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13. Draw the structure of the amino acid lysine showing the correct protonation states of its acid and base
functional groups in a solution of lysine at pH 10.5. What is the net overall charge on lys at this pH?
14. Draw the structure of the amino acid lysine showing the correct protonation states of its acid and base
functional groups in a solution of lysine at pH 8.5. What is the net overall charge on lys at this
→ Practice other questions like sample questions 12-14 using the 20 amino acids at varying pHs!!! (eg.
pH?
"Draw the structure of the amino acid Histidine showing the correct protonation states of its acid and base
functional groups in a solution of his at pH 5. What is the net overall charge on his at this pH?" etc...)
Transcribed Image Text:13. Draw the structure of the amino acid lysine showing the correct protonation states of its acid and base functional groups in a solution of lysine at pH 10.5. What is the net overall charge on lys at this pH? 14. Draw the structure of the amino acid lysine showing the correct protonation states of its acid and base functional groups in a solution of lysine at pH 8.5. What is the net overall charge on lys at this → Practice other questions like sample questions 12-14 using the 20 amino acids at varying pHs!!! (eg. pH? "Draw the structure of the amino acid Histidine showing the correct protonation states of its acid and base functional groups in a solution of his at pH 5. What is the net overall charge on his at this pH?" etc...)
Expert Solution
Introduction-

“Since you have posted multiple questions, we will provide the solution only to the first question as per our Q&A guidelines. Please repost the remaining questions separately.”

Lysine is one of the essential amino acid. It is basic in nature because of the presence of an extra amino group.

pKa is defined as the pH at which different ionization forms of an ionizable functional group within a molecule are present in equal concentrations.

Proteins/Amino acids have a net charge that will predict the behavior of the protein/ amino acid in a particular environment (pH). The net charge on protein depends on two main factors that is-

  1. Total number of charged amino acids.
  2. pH of the environment  (Isoelectric point is a pH at which net charge is zero).

 

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