Suppose you have a peptide composed of 4 amino acids bonded together: alanine, arginine, asparagine, and the novel amino acid armadillamine, which has an ionizable side group with a pKa of 7.2. At pH 9.5, this peptide has a net charge of -1. What is the charge on the protonated form of the armadillamine side group? Explain how you determined the charge on the protonated armadillamine side group)

Q: a. What is the charge of the primary structure of proteins at pH = 2.0, 4.0, 6.0 and 11.0 of the…

A: Note: Since we only answer up to 3 sub-parts, we will answer the first question and its subparts.…

Q: On the diagram above, draw a line across each peptide bond in oligopeptide 3a. Write the…

A: Since you have asked multiple questions, we will solve the first three question for you. If you want…

Q: Now let us look at a real amino acid, alanine. Fill in the chart below for each ionizable group. You…

A: Amino acids are the building block of proteins. Amino acids are consisted of carboxyl group, amine…

Q: Draw the tetrapeptide WERP at pH 7.2, with the C-terminal peptide bond in the cis conformation

A: Biomolecules are organic molecules made up of mainly carbon and hydrogen but there are other…

Q: At pH-4, what is the net charge of the peptide GKPAD? O+0.5 O-1.0 Oo -0.5

A: The sequence of the given peptide is as follows: Gly-Lys-Pro-Ala-Asp The amino acids are composed of…

Q: Trypsin is a digestive enzyme that hydrolyzes peptide bonds only when the carbonyl group in the…

A: Summary of Answers:Hydrolysis by Trypsin:Fragments: Gly—Lys, Arg, Ala—Ala, ArgPhenylalanine…

Q: A. Draw the structure of the following peptide sequence at pH 2.0: ASP-ALA-THR-LYS-GLY B. What is…

A: Amino acids are basic building blocks of polypeptides, and one or more of these polypeptides they…

Q: Calculate the isoelectric point of the tetrapeptide Ser-Leu-Phe-Pro at pH 7.0

A: Amino acid sequences are written with N-terminal amino acid on the left and C-terminal amino acid on…

Q: Is this the correct answer of finding what the charge is?

A: Amino acids are the smallest units that make up the peptides or proteins inside the cell. Twenty…

Q: A postgraduate student was given the task of predicting the 1H NMR spectrum for compound A.

A:

Q: Draw a peptide that includes Phenylalanine, Cysteine, Tyrosine and Tryptophan. Label them by name…

A: Draw a peptide that includes Phenylalanine, Cysteine, Tyrosine and Tryptophan. Label them by name…

Q: draw the primary structure of the polypeptide at physiological pH range of 7/35-7/45 using…

A: Polypeptide chains are composed of amino acids bonded to each other via peptide bonds. The N and C…

Q: 1. Draw an approximate titration curve of the following amino acid. Label the approximate…

A: The titration curve is a plot that tracks the behavior of amino acids under the influence of…

Q: Ferritin is treated with SDS or SDS and b-mercaptoethanol and subjected to polyacrylamide gel…

A: SDS PAGE is used to separate proteins based on their size. SDS is an anionic detergent that imparts…

Q: HENRY is a peptide sequence.  1) Draw the structure of the HENRY peptide as it exists at pH 7. Be…

A: Peptides are composed of amino acids joined to each other via peptide bonds. Peptides can have one…

Q: Peptide ionization Consider a peptide with the sequence Ser-His-Glu-Cys-Arg-Gln. You will be asked…

A: The net charge of the each amino acid residue in a peptide is determined by the side chain pK of the…

Q: 4) Using the pK, data found in the supplied chart, determine the predominant charge of each amino…

A: Amino acid is amphoteric in nature i.e it can act as both acid as well as . This property is due…

Q: 2) For the following amino acids, encircle those with a net charge of -2 at high pH underline those…

A: Alanine, valine, leucine, and isoleucine are hydrophobic amino acids with an alkyl group in their…

Q: For the oligopeptide below Gly-Asp-Ser-Cys-His pKa of terminal amino group: 8.0 pKa of Asp: 4.1 pka…

A: The given oligopeptide is composed of glycine, aspartic acid, serine, cysteine, and histidine amino…

Q: Assume you have a long polypeptide chain of Ser-Asp dipeptides linked end to end.  Explain the…

A: Serine is described as an amino acid that is majorly used in the process of biosynthesis of…

Q: 54. If an amino acid chain twists and turns into a tightly wound structure, choose the correct…

A: Folding of a protein properly to its correct 3D native conformation is the most important process…

Q: if two polypeptide chains are interacting as alpha helices with the following amino profiles: A:…

A: if two polypeptide chains are interacting as alpha helices with the following amino profiles: A:…

Q: 1. Consider the peptides P-A-I-G-E and M-A-T-T. a. Draw the structure of each peptide at a pH of 7.0…

A: Formation of the peptide bond neutralises any charge due to the alpha-amino group and alpha-carboxyl…

Q: Only 0.1% of peptide bonds have the cis configuration. Calculate the difference in energy between a…

A: A peptide bond is formed between the alpha carboxyl group of the amino acid residue at the N…

Q: Protein A is made up of a single polypeptide chain; The molecular mass of A is 20,000 Da; the A…

A: Protein has various levels of the organization. The primary structure of protein consists only of…

Q: Determine the net charge on the following pentapeptide "Lys-Ala-His-Asp-Ser" at: a. pH 1.0 b. pH…

A: The estimated charge on the given Lys-Ala-His-Asp-Ser peptide is +3.At low pH, the amino acid is…

Q: You have discovered a new amino acid that you name in honor of your favorite course.…

A: The titration curve of an amino acid shows the change in pH as an acid or base is added to the…

Q: Ala-Phe-Pro-Cys-Clu-Arg-Arg-Pro-His-Gly-Lys-Clu Calculate the net charge on the polypeptide at a.…

A: Note: There is no amino acid with a three-letter code as Clu. The charge calculation will be carried…

Q: list the amino acids that will carry a net charge at pH 7 within a protein. What is the charge at pH…

A: Note : Hi ! Thank you for the question. We are authorized to answer one question at a time. Since…

Q: 46. All hydrophobic amino acids share which of the following properties? A. Acidic R groups B.…

A: Amino acids are basic subunit of protein or polypeptide chain which is linked by peptide/amide bond…

Q: Determine the net charge of the following peptide at pH 10 given the respective pKa's. DDDMCRVNAY…

A: The peptide is the sequence of amino acids that are joined by the formation of peptide bond between…

Q: 2. With the help of the internet and your textbook, A. hand-draw the chemical structures of…

A: DPPC consist of two C₁₆ palmitic acid groups attached to a phosphatidylcholine head-group. It is…

Q: The E. coli enzyme triose phosphate isomerase has a pI of 5.7. What would the charge on this enzyme…

A: Isoelectric point refers to the value of pH (potential of hydrogen ions) of a molecule or enzyme at…

Q: draw the primary structure of the polypeptide at physiological pH range of 7.35-7.45 using…

A: A polypeptide is an amino acid chain molecule where the carboxyl group of one amino acid is linked…

Q: 5 For the peptide structure in #3, (ASP-ALA-THR-LYS-GLY), use the chart at the end of this HW set…

A: The proteins are composed of twenty naturally occurring amino acids.  The amino acids can be…

Q: a peptide has the sequence: Asp-His-Tyr-Asn. What is the net charge on this molecule at pH 7.2?

A: Given peptide has the sequence Asp-His-Tyr-Asn. The net charge on this peptide depends upon the pKa…

Q: Draw a structural formula for each nucleotide and estimate its net charge at pH 7.4, the pH of blood…

A: Nucleotides are the monomers of nucleic acids, DNA and RNA. A nucleotide is composed of a…

Q: Draw a structural formula for the form of each amino most prevalent at pH 10.0. Q.) Aspartic acid

A: Aspartic acid is a negatively charged amino acid used in the synthesis of proteins. At physiological…

Q: 5. Refer to Model 2 for information relevant to this question. A sample of the peptide Lys net…

A: Amino acids are organic compound having two functional group namely carboxyl and amino group. Some…

Q: What is the net charge on the peptide RHTLE at pH 12.5?

A: Amino acids have ionizable groups in them. All ionizable groups have their characteristic pKa…