HENRY is a peptide sequence. 1) Draw the structure of the HENRY peptide as it exists at pH 7. Be sure to label any and all charges. You can neglect the stereochemistry at the α carbon. 2) Now consider the longer peptide HENRYLINK. What is its charge at pH 7 and how does this charge compare to the charge of the HENRY peptide at pH 7? 3) Finally, draw a helical wheel diagram for the HENRYLINK peptide. How many turns of an α-helix does it encompass? Is the peptide amphipathic? Explain why or why not in a few sentences.
HENRY is a peptide sequence. 1) Draw the structure of the HENRY peptide as it exists at pH 7. Be sure to label any and all charges. You can neglect the stereochemistry at the α carbon. 2) Now consider the longer peptide HENRYLINK. What is its charge at pH 7 and how does this charge compare to the charge of the HENRY peptide at pH 7? 3) Finally, draw a helical wheel diagram for the HENRYLINK peptide. How many turns of an α-helix does it encompass? Is the peptide amphipathic? Explain why or why not in a few sentences.
Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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HENRY is a peptide sequence.
1) Draw the structure of the HENRY peptide as it exists at pH 7. Be sure to label any and all charges. You can neglect the stereochemistry at the α carbon.
2) Now consider the longer peptide HENRYLINK. What is its charge at pH 7 and how does this charge compare to the charge of the HENRY peptide at pH 7?
3) Finally, draw a helical wheel diagram for the HENRYLINK peptide. How many turns of an α-helix does it encompass? Is the peptide amphipathic? Explain why or why not in a few sentences.
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