What is the isoelectric point for the peptide STVWY at pH 13? Draw the structure. Connect the carbonyl with the N-terminus residue to the NH to be hydrogen bonded if the peptide formed an alpha helix.
What is the isoelectric point for the peptide STVWY at pH 13? Draw the structure. Connect the carbonyl with the N-terminus residue to the NH to be hydrogen bonded if the peptide formed an alpha helix.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Question
What is the isoelectric point for the peptide STVWY at pH 13? Draw the structure. Connect the carbonyl with the N-terminus residue to the NH to be hydrogen bonded if the peptide formed an alpha helix.
Expert Solution
Step 1
The isoelectric point of a protein can be defined as the pH at which the net charge of the protein is zero. At this point, the protein acts as a zwitter ion and is in the most stable form. The net charge of the protein depends on the pKa values of the side chains of the amino acids that form the protein.
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