K₁ = α [H+][A-] [HA] [A-] pH = pK+log [HA] 1-1 The Amino acid Arginine ionizes according to the scheme below. Calculate the isoelectric point of Arginine and the average charge on arginine when pH = 9.2. NH2 H C=N NH pka-2.17 -H' NH2 H C=N H NH PK-8.99 -H +H* H (CH2)3 H-N-C-COOH | H H +H* H (CH2)3 H-N-C-coo- H H Ans: 10.75; +0.38 NH2 NH2 H C=N C=N-H H NH PK-12.5 -H NH | +H* (CH2)3 H₂N-C-COO- | H III (CH2)3 H₂N-C COO- H IV

K₁ = α [H+][A-] [HA] [A-] pH = pK+log [HA] 1-1 The Amino acid Arginine ionizes according to the scheme below. Calculate the isoelectric point of Arginine and the average charge on arginine when pH = 9.2. NH2 H C=N NH pka-2.17 -H' NH2 H C=N H NH PK-8.99 -H +H* H (CH2)3 H-N-C-COOH | H H +H* H (CH2)3 H-N-C-coo- H H Ans: 10.75; +0.38 NH2 NH2 H C=N C=N-H H NH PK-12.5 -H NH | +H* (CH2)3 H₂N-C-COO- | H III (CH2)3 H₂N-C COO- H IV

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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