peptide Lys-Glu-Trp answer the following questions: Draw the structure of this peptide when all the ionizable groups are fully protonated. How many ionizable groups does this peptide have? Label the pKa for each of the ionizable groups in the structure above. Draw the appropriate titration curve for this peptide on graph paper starting at pH 0 and ending at pH 14. Label the x-axis, y-axis and the pKa Determine the overall net charge of this peptide at each full equivalent point (including 0) where the ionizable group is 100% deprotonated. Determine the pI for this peptide. Determine the average overall net charge of a mixture of this peptide in a solution where pH=8.5.
peptide Lys-Glu-Trp
answer the following questions:
Draw the structure of this peptide when all the ionizable groups are fully protonated.
How many ionizable groups does this peptide have? Label the pKa for each of the ionizable groups in the structure above.
Draw the appropriate titration curve for this peptide on graph paper starting at pH 0 and ending at pH 14. Label the x-axis, y-axis and the pKa
Determine the overall net charge of this peptide at each full equivalent point (including 0) where the ionizable group is 100% deprotonated.
Determine the pI for this peptide.
Determine the average overall net charge of a mixture of this peptide in a solution where pH=8.5.
![TABLE 5.1 Properties of the common amino acids found in proteins
Name
Abbreviations 1-
pk of
and 3-letter codes
pka of
pK₂ of lonizing
a-COOH Group a-NH3 Group Side Chain
A, Ala
9.7
R, Arg
9.0
N, Asn
8.8
9.8
10.8
9.1
9.7
9.6
9.2
9.7
9.6
9.0
9.2
9.1
10.6
9.2
10.4
9.4
9.1
9.6
Alanine
Arginine
Asparagine
Aspartic acid
Cysteine
Glutamine
Glutamic acid
Glycine
Histidine
Isoleucine
Leucine
Lysine
Methionine
Phenylalanine
Proline
Serine
Threonine
Tryptophan
Tyrosine
Valine
D, Asp
C, Cys
Q, Gin
E, Glu
G, Gly
H, His
I, lle
L, Leu
K, Lys
M, Met
F, Phe
P, Pro
S, Ser
T, Thr
W, Trp
Y, Tyr
V, Val
2.3
2.2
2.0
2.1
1.8
2.2
2.2
2.3
1.8
2.4
2.4
2.2
2.3
1.8
2.0
2.2
2.6
2.4
2.2
2.3
12.5
3.9
8.3
-
4.2
6.0
-
-
10.0
10.1
-](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F8199c86a-9a43-4e88-9764-a89d45cdee6b%2F39ca45a7-0112-4963-b502-1e0773055fee%2Fvwiuawy_processed.png&w=3840&q=75)
![](/static/compass_v2/shared-icons/check-mark.png)
Trending now
This is a popular solution!
Step by step
Solved in 3 steps with 6 images
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
![Human Heredity: Principles and Issues (MindTap Co…](https://www.bartleby.com/isbn_cover_images/9781305251052/9781305251052_smallCoverImage.gif)
![Human Heredity: Principles and Issues (MindTap Co…](https://www.bartleby.com/isbn_cover_images/9781305251052/9781305251052_smallCoverImage.gif)