On the diagram above, draw a line across each peptide bond in oligopeptide 3a. Write the single-letter sequence. On the diagram above, circle all the chiral centres in oligopeptide 3a. Complete the Table below to indicate, for oligopeptide 3a, the charges on ionisable groups and the net overall charge at pH 7 and at pH 11. What moieties within oligopeptide 3a are those mainly responsible for the formation of an alpha-helix? Name the process that leads to the unfolding of the alpha helix to yield a random coil. State and justify, for oligopeptide 3a, which amino acid side chains will be involved in: hydrophilic interactions, hydrophobic interactions, disulphide bridges and salt bridges. In each case, briefly justify your choice.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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  1. On the diagram above, draw a line across each peptide bond in oligopeptide 3a. Write the single-letter sequence.
  2. On the diagram above, circle all the chiral centres in oligopeptide 3a.
  3. Complete the Table below to indicate, for oligopeptide 3a, the charges on ionisable groups and the net overall charge at pH 7 and at pH 11.
  4. What moieties within oligopeptide 3a are those mainly responsible for the formation of an alpha-helix? Name the process that leads to the unfolding of the alpha helix to yield a random coil.
  5. State and justify, for oligopeptide 3a, which amino acid side chains will be involved in: hydrophilic interactions, hydrophobic interactions, disulphide bridges and salt bridges. In each case, briefly justify your choice.
За
H₂N
0
NH₂
NH
НО
H2N,
NH
NH
NH
OH
SH
NH
S
NH
OH
Transcribed Image Text:За H₂N 0 NH₂ NH НО H2N, NH NH NH OH SH NH S NH OH
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