7. Aspartic acid has a side chain bearing a carboxylic acid group; its pK, is 4. The a-amino and a-carboxylic groups have pK, values similar to those of alanine. Determine the net charge on aspartic acid at the following pH values: pH 1 pH 2 pH 4 pH 9 pH 13
Nucleotides
It is an organic molecule made up of three basic components- a nitrogenous base, phosphate,and pentose sugar. The nucleotides are important for metabolic reactions andthe formation of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
Nucleic Acids
Nucleic acids are essential biomolecules present in prokaryotic and eukaryotic cells and viruses. They carry the genetic information for the synthesis of proteins and cellular replication. The nucleic acids are of two types: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The structure of all proteins and ultimately every biomolecule and cellular component is a product of information encoded in the sequence of nucleic acids. Parts of a DNA molecule containing the information needed to synthesize a protein or an RNA are genes. Nucleic acids can store and transmit genetic information from one generation to the next, fundamental to any life form.
 alt="6. Using the charges you calculated above, plot the characteristics of alanine over a range of pH
values. Connect the points by estimating what the charge should be at pH values where you
lack data. It is possible to calculate the charge at any pH, but if you understand the
relationships presented here you will be able to make estimates quickly and easily.
+2
+1.5
+1 -
+0.5-
-0.5 -
-1-
-1.5 -
7.
6.
11
13
14
pH of solution
7. Aspartic acid has a side chain bearing a carboxylic acid group; its pK, is 4. The a-amino and
a-carboxylic groups have pKa values similar to those of alanine. Determine the net charge
on aspartic acid at the following pH values:
pH 1
pH 2
pH 4
pH 9
pH 13
Net charge of molecules
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