Lab 05 Assignment2 (1)

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Wilfrid Laurier University *

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Chemistry

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Apr 3, 2024

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1 Name: Sanya Jain ID: 169041804 Lab Day and Time: Friday 10:30 Lab #5 Muscle Physiology Assignment Data Submission: As a group , using your data from Exercise Twitch Response and Recruitment, graph the Stimulus Intensity versus the Twitch Peak Force output. (Submitted via Dropbox, as a group, due at 11:59pm) (4 marks) In Lab Assignment: 1. What is the relationship between the Stimulus Strength and the Twitch Peak Force according to your data? (1 mark) They are directly proportional to each other, therefore a positive correlation. The twitch peak force id dependent on the stimulus intensity. 2. What is the physiological basis of this relationship? (What is happening in the body to cause the response, and why is the response changing as the stimulus strength changes)? (2 marks) Response may change due to an alteration in the release of calcium concentration , which can be held responsible for muscles effective force. The action potential produced at the muscle fibers due to the colin release, which cause the release of calcium ions within the muscle cells, which leads to muscle contractions. The sliding filament mechanism, actin and myosin filaments interact to produce force and cause muscle contraction, depends on these calcium ions. More motor neurons are recruited which leads to higher potentials, higher force. 3. During data collection, at the lower stimulus strengths, did you have any occurrences where you applied a stimulus but no response was observed? What is the physiological reason for this? (1 mark) No, there was no response. Since the threshold wasn’t bad. A lower twitch peak force arises from the activation of merely smaller motor units in the aftermath of a low stimulus strength, whilst a greater stimulus strength triggers the recruitment of both smaller and stronger motor units, generating a higher twitch peak force.
2 4. During data collection, at the higher stimulus strengths, did you have any occurrences where multiple stimuli of varying strength elicited roughly the same response? What is the physiological reason for this? (1 mark) Yes, we have One threshold, action potential is same for all, so its roughly same because we can’t have higher depolarization. The rate of rise in force generation, however, becomes less steep as one approaches higher stimulus levels and finally reaches a plateau. a greater stimulus strength triggers the recruitment of both smaller and stronger motor units, generating a higher twitch peak force. 5. List your recorded values below (2 marks) Participant A Participant B Stimulus Amplitude (mA) Twitch Peak Force (mV) 5 0 6 0 7 0 8 14.27591000000001 9 30.257464 10 19.0857047 11 3.96042 12 34.89508 13 13.2125781 14 0 15 0 16 0 17 219.44144531 18 97.73544220000001 19 184.75091 20 184.75091 Stimulus Amplitude (mA) Twitch Peak Force (mV) 5 38.19764 6 59.4204718689 7 82.6973 8 83.77398000000001 9 73.76626 10 62.02941 11 51.8083 12 52.37611 13 56.50695299999996 14 51.399727 15 71.78681 16 90.2346 17 65.18745 18 50.59515 19 40.97671000000004 20 86.0194 6. According to the Summation Exercise, why does the peak force of the 2nd force response increase as the time between stimulation pulses decreases? Specifically what
3 happens within the muscle fiber to make the second and third responses bigger than the first response? (4 marks) The second response increases because first one doesn’t go up due to the The number of fibres engaged, the size of the recruited muscle fibres, the frequency of stimulation, and contracting at the ideal muscle length are the factors that affect force output. The extent of muscle fibres recruited for contraction is modulated by the intensity of the stimulus provided to the muscle fibres. The size principle describes how the stimulus strength and twitch peak force relate. This gives insight that when muscles contract, motor units with smaller fibres within muscles are engaged initially, along the time stimulus strength increases, motor units with bigger muscle fibres follow. Larger motor units produce more force than smaller ones usually correlated with lesser force generation. . The action potential produced at the muscle fibers due to the colin release, which cause the release of calcium ions within the muscle cells, which leads to muscle contractions. The sliding filament mechanism, actin and myosin filaments interact to produce force and cause muscle contraction, depends on these calcium ions.
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