Lab 05 Assignment2 (1)
pdf
keyboard_arrow_up
School
Wilfrid Laurier University *
*We aren’t endorsed by this school
Course
320
Subject
Chemistry
Date
Apr 3, 2024
Type
Pages
3
Uploaded by ColonelAnteaterMaster214
1 Name: Sanya Jain
ID: 169041804 Lab Day and Time: Friday 10:30 Lab #5 Muscle Physiology Assignment Data Submission: As a group
, using your data from Exercise Twitch Response and Recruitment, graph the Stimulus Intensity versus the Twitch Peak Force output. (Submitted via Dropbox, as a group, due at 11:59pm) (4 marks) In Lab Assignment: 1. What is the relationship between the Stimulus Strength and the Twitch Peak Force according to your data? (1 mark) They are directly proportional to each other, therefore a positive correlation. The twitch peak force id dependent on the stimulus intensity. 2. What is the physiological basis of this relationship? (What is happening in the body to cause the response, and why is the response changing as the stimulus strength changes)? (2 marks) Response may change due to an alteration in the release of calcium concentration , which can be held responsible for muscles effective force. The action potential produced at the muscle fibers due to the colin release, which cause the release of calcium ions within the muscle cells, which leads to muscle contractions. The sliding filament mechanism, actin and myosin filaments interact to produce force and cause muscle contraction, depends on these calcium ions. More motor neurons are recruited which leads to higher potentials, higher force. 3. During data collection, at the lower stimulus strengths, did you have any occurrences where you applied a stimulus but no response was observed? What is the physiological reason for this? (1 mark) No, there was no response. Since the threshold wasn’t bad. A lower twitch peak force arises from the activation of merely smaller motor units in the aftermath of a low stimulus strength, whilst a greater stimulus strength triggers the recruitment of both smaller and stronger motor units, generating a higher twitch peak force.
2 4. During data collection, at the higher stimulus strengths, did you have any occurrences where multiple stimuli of varying strength elicited roughly the same response? What is the physiological reason for this? (1 mark) Yes, we have One threshold, action potential is same for all, so its roughly same because we can’t have higher depolarization. The rate of rise in force generation, however, becomes less steep as one approaches higher stimulus levels and finally reaches a plateau. a greater stimulus strength triggers the recruitment of both smaller and stronger motor units, generating a higher twitch peak force. 5. List your recorded values below (2 marks) Participant A Participant B Stimulus Amplitude (mA) Twitch Peak Force (mV) 5 0 6 0 7 0 8 14.27591000000001 9 30.257464 10 19.0857047 11 3.96042 12 34.89508 13 13.2125781 14 0 15 0 16 0 17 219.44144531 18 97.73544220000001 19 184.75091 20 184.75091 Stimulus Amplitude (mA) Twitch Peak Force (mV) 5 38.19764 6 59.4204718689 7 82.6973 8 83.77398000000001 9 73.76626 10 62.02941 11 51.8083 12 52.37611 13 56.50695299999996 14 51.399727 15 71.78681 16 90.2346 17 65.18745 18 50.59515 19 40.97671000000004 20 86.0194 6. According to the Summation Exercise, why does the peak force of the 2nd force response increase as the time between stimulation pulses decreases? Specifically what
3 happens within the muscle fiber to make the second and third responses bigger than the first response? (4 marks) The second response increases because first one doesn’t go up due to the The number of fibres engaged, the size of the recruited muscle fibres, the frequency of stimulation, and contracting at the ideal muscle length are the factors that affect force output. The extent of muscle fibres recruited for contraction is modulated by the intensity of the stimulus provided to the muscle fibres. The size principle describes how the stimulus strength and twitch peak force relate. This gives insight that when muscles contract, motor units with smaller fibres within muscles are engaged initially, along the time stimulus strength increases, motor units with bigger muscle fibres follow. Larger motor units produce more force than smaller ones usually correlated with lesser force generation. . The action potential produced at the muscle fibers due to the colin release, which cause the release of calcium ions within the muscle cells, which leads to muscle contractions. The sliding filament mechanism, actin and myosin filaments interact to produce force and cause muscle contraction, depends on these calcium ions.
Your preview ends here
Eager to read complete document? Join bartleby learn and gain access to the full version
- Access to all documents
- Unlimited textbook solutions
- 24/7 expert homework help
Related Questions
Carbachol causes contractions the isolated rat ileum to contract. The responses obtained
to increasing concentrations of carbachol are tabulated below. Graph the data as log
concentration versus % maximum response, using Excel or another spreadsheet
program. Use the graph to estimate the EC50 value for carbachol and indicate its position
on the graph.
Conc (M)
Exp 1
Exp 2
Exp 3
(% max response)
(% max response)
(% max response)
1.00E-09
3.00E-09
10
20
1.00E-08
45
35
48
3.00E-08
57
69
72
1.00E-07
74
81
91
3.00E-07
95
85
96
1.00E-06
100
100
99
3.00E-06
100
98
99
arrow_forward
1. Define the following terms in the context of Drug Discovery and Development. (2 pts each)
(a) Target
(b) Hit
(c) Lead
(d) Lead Optimization
(e) Investigational New Drug (IND)
(f) New Drug Application (NDA)
(g) Pharmacodynamics
(h) Pharmacokinetics
(i) Absorption
(j) Distribution
(k) Metabolism
(I) Excretion
(m) Toxicity
(n) Phenotype-based drug discovery
(o) Target-based drug discovery
arrow_forward
A direct enzyme-linked immunosorbent assay (ELISA) test on a patient's sample is shown below. Development of a strong (dark) color reaction would indicate:
1 Antibody is adsorbed to well. 2 Patient sample is added;
complementary antigen
binds to antibody.
3 Enzyme-linked antibody specific 4 Enzyme's substrate () is added,
for test antigen is added and binds and reaction produces a product
that causes a visible color change (O).
to antigen, forming sandwich.
A low concentration of a specific antigen in the patient's sample
O A high concentration of a specific enzyme in the patient's sample
The patient's antibody is specific for the enzyme's substrate
O A high concentration of a specific antigen in the patient's sample
A high concentration of a specific antibody (against the test antigen) in the patient's sample
arrow_forward
Subpart 1-5
arrow_forward
analyte
concentration(C)(mg/ml)
injection volume (ul)
elution time (time)
peak DAD signal(mAU)
caffeine
1
1
4.67
302.85
aspartame
5
1
7.53
15.83
benzoic acid
1
1
8.14
89.98
saccharin
1
1
1.91
84.86
mixture(add everything above with 1:1:1:1 ratio)
1
4.47
69.58
How to get the concentration of the mixture in this case?
arrow_forward
I need help with my homework
arrow_forward
E-book - Elementary Bioorgani ×
My Course - Elementary Bioorg X
endocrine system - Google Do X
Homework 1 Matter and Materia X
Question 12 of 23 - Homework X
assessments.macmillanlearning.com/sac/5338340#/5338340/11/1
Update :
O Assignment Score:
Lx Give Up?
O Hint
Check Answer
52.2%
Resources
< Question 12 of 23
Attempt 3
Carry out the given conversions from one metric unit of length to another.
83.5 Mm =
km
4.75 nm =
mm
* TOOLS
х10
!!!
arrow_forward
OnCourse Connect
Assessment: Chemistry x
4 Copy of spread of jslar x
E The Spread of Islam - G x
M Inbox (904) - aarojame: x
A Classes
oncourseconnect.com/assessment/1651879/5287e2a3-0d0b-e2c0-c15c-3e68a37149b4
O TPSS Bookmarks
CHEMISTRY BENCHMARK TEST 01
CHEMISTRY I 12-7 (AARON JAMES, ID: 12390724)
Potassium (K) reacts with oxygen gas (O,) to form potassium oxide (K,O). Which equation for this reaction is correctly balanced?
K+O2 K,0
2K + O2 K20
4K+ O2 2K20
4K+202 2K,0
35
Save/Exit
26 27 28 29 30 31 3R 33 34
ttps://www.oncourseconnect.com/assessment/1651879/5287e2a3-0d0b-e2c0-c15c-3e68a37149b4#
B.
arrow_forward
Styles
Voice
Text in Portuguese is not being checked. Do you
(i) MISSING PROOFING TOOLS want to download proofing tools and future
Sensitivity
Editon
Download
updates?
一
4
7.
10 1
11
| 12
17. What is the main side effect of anti-epileptic drugs?
a. Hypertension
b. Drowsiness
c. Tachycardia
I.
d. Insomnia
e. Euphoria
I believe these drugs are like the ones of the work- dihidropyridines-cont
18. What is metformin used for as first choice of treatment, and why?
a. Type II diabetes, because it regulates blood glucose levels
b. Hyperthyroidism, because it inhibits the formation of T3 an
idirm hecause it doesn't interact with other drug
9.1
7.
8.
arrow_forward
hi please help me with this problem need it until 9:06 am thank you. Kindly please make it short, not long. thank you soo much
fROM THE PICTURE (A) Write down 10 hazards that you can observe in the said picture. (B) Identify the type or category of hazard (physical, chemical, microbiological, allergenic) that you observed and write its category beside the name of the corresponding hazard. To facilitate the checking of your answers, number them accordingly (1 to 10). Example: 1. nail - physical *
arrow_forward
1) Which of the diet sodas have the highest concentration of caffeine? Which standard best reflects this concentration?
arrow_forward
V. Error Analysis/Questions For the following questions explain what specific error in calculating your Ksp value would occur (i.e. would the Ksp be too HIGH or too LOW), compared to the situation in which no errors occur. When you answer the question, consider how the situation affects the calculation of Ksp. Each answer must have an explanation and type the answer, please.
A. The buret was not conditioned (it still had water in it) when you add the HCl. Would the Ksp be too HIGH or too LOW?
B. There was Ca(OH)2 solid (that was not filtered off) in your solution to be titrated. Would the Ksp be too HIGH or too LOW?
C. You measured 24.00 mL of Ca(OH)2 solution instead of 25.00 mL. Would the Ksp be too HIGH or too LOW?
D. The HCl concentration was actually lower than the reported molarity on the bottle. Would the Ksp be too HIGH or too LOW?
arrow_forward
Please refer to the image attached below and answer the following question. Thanks
What referrals would you give to her and in what order?
arrow_forward
Rb Blackboard Collaborate Ultra -2 x
General Psychology -Fall 20
How to Find a Career Path Using X
V What Kind of Intelligence Do You X
A ALEKS - Griffin Barden- Learn
com/alekscgi/x/Isl.exe/1o_u-IgNslkr7j8P3jH-IJcZzdcvSCzsqTCIDqNGV3bKqhMfPmUcQ4ENkmiXn9QCwgeDPDkQ06yszYWESPcekwL0-Qg6l19rekU7404HgFAGBEZaDr080?1oBw7QYjlbavbSPXtx-YCjsh_7mMmrq
O THERMOCHEMISTRY
Griffin
Calculating a molar heat of reaction from formation enthalpies
Using the table of standard formation enthalpies that you'll find under the ALEKS Data tab, calculate the reaction enthalpy of this reaction under standard
conditions:
(6)°Hɔ-(5)
arrow_forward
EQD₂ = nd*
α
Assume a/B
(d+(a/B))
(2+(a/B))
BED:= (nd)*(1+
α
=2 for late effects and a/B 10 for acute effects
1. Using the Equivalent Dose in 2 Gy Fractions equation, compare the following protocols. Which would have better
tumor control? Which would have worse late effects?
42 Gy delivered in 12 fractions; 30 Gy delivered in 5 fractions.
arrow_forward
charting costs ($) -
T T TTT T
2.
On the graph shown to the right:
(a) Draw a star (*) on the
abscissa.
120
110
100
(b) Draw a diamond (O) on
the ordinate.
90
9 80
70
(c) Draw a circle around the
dependent variable.
60
50
40
30
(d) Draw a small arrow point-
ing to a tic mark.
20
10
25
30
35
(e) Circle the origin.
10
16
20
number of patiernts
arrow_forward
SEE MORE QUESTIONS
Recommended textbooks for you

Chemistry
Chemistry
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning

Chemistry
Chemistry
ISBN:9781259911156
Author:Raymond Chang Dr., Jason Overby Professor
Publisher:McGraw-Hill Education

Principles of Instrumental Analysis
Chemistry
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Cengage Learning

Organic Chemistry
Chemistry
ISBN:9780078021558
Author:Janice Gorzynski Smith Dr.
Publisher:McGraw-Hill Education

Chemistry: Principles and Reactions
Chemistry
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:Cengage Learning

Elementary Principles of Chemical Processes, Bind...
Chemistry
ISBN:9781118431221
Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:WILEY
Related Questions
- Carbachol causes contractions the isolated rat ileum to contract. The responses obtained to increasing concentrations of carbachol are tabulated below. Graph the data as log concentration versus % maximum response, using Excel or another spreadsheet program. Use the graph to estimate the EC50 value for carbachol and indicate its position on the graph. Conc (M) Exp 1 Exp 2 Exp 3 (% max response) (% max response) (% max response) 1.00E-09 3.00E-09 10 20 1.00E-08 45 35 48 3.00E-08 57 69 72 1.00E-07 74 81 91 3.00E-07 95 85 96 1.00E-06 100 100 99 3.00E-06 100 98 99arrow_forward1. Define the following terms in the context of Drug Discovery and Development. (2 pts each) (a) Target (b) Hit (c) Lead (d) Lead Optimization (e) Investigational New Drug (IND) (f) New Drug Application (NDA) (g) Pharmacodynamics (h) Pharmacokinetics (i) Absorption (j) Distribution (k) Metabolism (I) Excretion (m) Toxicity (n) Phenotype-based drug discovery (o) Target-based drug discoveryarrow_forwardA direct enzyme-linked immunosorbent assay (ELISA) test on a patient's sample is shown below. Development of a strong (dark) color reaction would indicate: 1 Antibody is adsorbed to well. 2 Patient sample is added; complementary antigen binds to antibody. 3 Enzyme-linked antibody specific 4 Enzyme's substrate () is added, for test antigen is added and binds and reaction produces a product that causes a visible color change (O). to antigen, forming sandwich. A low concentration of a specific antigen in the patient's sample O A high concentration of a specific enzyme in the patient's sample The patient's antibody is specific for the enzyme's substrate O A high concentration of a specific antigen in the patient's sample A high concentration of a specific antibody (against the test antigen) in the patient's samplearrow_forward
- Subpart 1-5arrow_forwardanalyte concentration(C)(mg/ml) injection volume (ul) elution time (time) peak DAD signal(mAU) caffeine 1 1 4.67 302.85 aspartame 5 1 7.53 15.83 benzoic acid 1 1 8.14 89.98 saccharin 1 1 1.91 84.86 mixture(add everything above with 1:1:1:1 ratio) 1 4.47 69.58 How to get the concentration of the mixture in this case?arrow_forwardI need help with my homeworkarrow_forward
- E-book - Elementary Bioorgani × My Course - Elementary Bioorg X endocrine system - Google Do X Homework 1 Matter and Materia X Question 12 of 23 - Homework X assessments.macmillanlearning.com/sac/5338340#/5338340/11/1 Update : O Assignment Score: Lx Give Up? O Hint Check Answer 52.2% Resources < Question 12 of 23 Attempt 3 Carry out the given conversions from one metric unit of length to another. 83.5 Mm = km 4.75 nm = mm * TOOLS х10 !!!arrow_forwardOnCourse Connect Assessment: Chemistry x 4 Copy of spread of jslar x E The Spread of Islam - G x M Inbox (904) - aarojame: x A Classes oncourseconnect.com/assessment/1651879/5287e2a3-0d0b-e2c0-c15c-3e68a37149b4 O TPSS Bookmarks CHEMISTRY BENCHMARK TEST 01 CHEMISTRY I 12-7 (AARON JAMES, ID: 12390724) Potassium (K) reacts with oxygen gas (O,) to form potassium oxide (K,O). Which equation for this reaction is correctly balanced? K+O2 K,0 2K + O2 K20 4K+ O2 2K20 4K+202 2K,0 35 Save/Exit 26 27 28 29 30 31 3R 33 34 ttps://www.oncourseconnect.com/assessment/1651879/5287e2a3-0d0b-e2c0-c15c-3e68a37149b4# B.arrow_forwardStyles Voice Text in Portuguese is not being checked. Do you (i) MISSING PROOFING TOOLS want to download proofing tools and future Sensitivity Editon Download updates? 一 4 7. 10 1 11 | 12 17. What is the main side effect of anti-epileptic drugs? a. Hypertension b. Drowsiness c. Tachycardia I. d. Insomnia e. Euphoria I believe these drugs are like the ones of the work- dihidropyridines-cont 18. What is metformin used for as first choice of treatment, and why? a. Type II diabetes, because it regulates blood glucose levels b. Hyperthyroidism, because it inhibits the formation of T3 an idirm hecause it doesn't interact with other drug 9.1 7. 8.arrow_forward
- hi please help me with this problem need it until 9:06 am thank you. Kindly please make it short, not long. thank you soo much fROM THE PICTURE (A) Write down 10 hazards that you can observe in the said picture. (B) Identify the type or category of hazard (physical, chemical, microbiological, allergenic) that you observed and write its category beside the name of the corresponding hazard. To facilitate the checking of your answers, number them accordingly (1 to 10). Example: 1. nail - physical *arrow_forward1) Which of the diet sodas have the highest concentration of caffeine? Which standard best reflects this concentration?arrow_forwardV. Error Analysis/Questions For the following questions explain what specific error in calculating your Ksp value would occur (i.e. would the Ksp be too HIGH or too LOW), compared to the situation in which no errors occur. When you answer the question, consider how the situation affects the calculation of Ksp. Each answer must have an explanation and type the answer, please. A. The buret was not conditioned (it still had water in it) when you add the HCl. Would the Ksp be too HIGH or too LOW? B. There was Ca(OH)2 solid (that was not filtered off) in your solution to be titrated. Would the Ksp be too HIGH or too LOW? C. You measured 24.00 mL of Ca(OH)2 solution instead of 25.00 mL. Would the Ksp be too HIGH or too LOW? D. The HCl concentration was actually lower than the reported molarity on the bottle. Would the Ksp be too HIGH or too LOW?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- ChemistryChemistryISBN:9781305957404Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCostePublisher:Cengage LearningChemistryChemistryISBN:9781259911156Author:Raymond Chang Dr., Jason Overby ProfessorPublisher:McGraw-Hill EducationPrinciples of Instrumental AnalysisChemistryISBN:9781305577213Author:Douglas A. Skoog, F. James Holler, Stanley R. CrouchPublisher:Cengage Learning
- Organic ChemistryChemistryISBN:9780078021558Author:Janice Gorzynski Smith Dr.Publisher:McGraw-Hill EducationChemistry: Principles and ReactionsChemistryISBN:9781305079373Author:William L. Masterton, Cecile N. HurleyPublisher:Cengage LearningElementary Principles of Chemical Processes, Bind...ChemistryISBN:9781118431221Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. BullardPublisher:WILEY

Chemistry
Chemistry
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning

Chemistry
Chemistry
ISBN:9781259911156
Author:Raymond Chang Dr., Jason Overby Professor
Publisher:McGraw-Hill Education

Principles of Instrumental Analysis
Chemistry
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Cengage Learning

Organic Chemistry
Chemistry
ISBN:9780078021558
Author:Janice Gorzynski Smith Dr.
Publisher:McGraw-Hill Education

Chemistry: Principles and Reactions
Chemistry
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:Cengage Learning

Elementary Principles of Chemical Processes, Bind...
Chemistry
ISBN:9781118431221
Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:WILEY