EQD₂ = nd* α Assume a/B (d+(a/B)) (2+(a/B)) BED:= (nd)*(1+ α =2 for late effects and a/B 10 for acute effects 1. Using the Equivalent Dose in 2 Gy Fractions equation, compare the following protocols. Which would have better tumor control? Which would have worse late effects? 42 Gy delivered in 12 fractions; 30 Gy delivered in 5 fractions.

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Ј.B. is a 52-year-old man weighing 72 kg who has been treated with gentamicin for confirmed gram-negative pneumonia. Design the dose of gentamicin (given in a one-hour infusion) to achieve Cmax = 10 mg / L and Cmin = 1.6 mg / L with values ​​for V = 18 L and t1 / 2 = 8 hours. please give me answer using pharmacokinetics!!! URGENT

AaBbCCL I Normal T No Spac. Heading 1 Heading 2 A . A- Styles Paragraph Alb ol o2 B Nephrotic Syndrome 1.3 A 60-year-old woman with the history of rheumatoid arthritis, smoking 60 packs/y, chronic obstructive pulmonary disease and treated hypertension underwent a screening colonoscopy and the felt poorly for a week. She saw a physician, who referred to the local clinic where they did a list of blood tests as indicated below: 業 Tests Results Ref ranges 3.7 mg/di 35mg/dl | 12.5 ml/min 148mg/dl 19mg/di Creatinine Females <1.2 BUN 5-20 Creatinine Clegrance 75-115 C3 80-200 C4 15-80 4.1 g/di positive Albumin 3.5-5 Cryoglobulin screen Serum protein electrophoresis (SPE)- polyclonal hyperalobinemia with no monoclonalimmunoglobulin spike identified. Urine sediment: no RBC, 4 8WBC's/hpt, granular and hyaline casts 1.3.1 What disease state is the most likely explanation for the patients results. Nephrocalcinosis 1.3.2 What is the clinical signiticance of polyclonal hypergammaglobunemia with no…