EQD₂ = nd* α Assume a/B (d+(a/B)) (2+(a/B)) BED:= (nd)*(1+ α =2 for late effects and a/B 10 for acute effects 1. Using the Equivalent Dose in 2 Gy Fractions equation, compare the following protocols. Which would have better tumor control? Which would have worse late effects? 42 Gy delivered in 12 fractions; 30 Gy delivered in 5 fractions.

2. What quantity should be dispensed when 50 mg of amitryptyline has been prescribed two times per day for 2 weeks, if the medication shown below is all that is available? Amitriptyline HCI Tablets, USP 25 mg 1000 TABLETS R only 0781-1487-10 6 Each tablet contains: Amitriptyline HCI, USP Usual Dosage: See package insert. Store at controlled room temperature 150-30°C (59⁰. 86°F). Dispense in a tight, light-resistant container. KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN. Rev. 09-2001M Manufactured By Geneva Pharmaceuticals, Inc. Broomfield, CO 80020 25 mg Geneva SPECIMEN PHARMACEUTICALS

4 (Chemical Connections 19F) Why do Lactomer stitches dissolve within 2 to 3 weeks following surgery?

Apatent that weights 180-b will take 40 mgkg of ammonium chioride How many millters of an ammonium chioride (N4Clnw. 53 5) injection containing 5 mEgim should be added to the patient's rtravenous infusion? ... Answers A-D A 94mi B 24 4ml 122m 6.1mi A patient that weighs 180 pounds will take 40 mg/kg of ammonium chloride. How many milliliters of an ammonium chloride NH4CI-m.w. 53.5 injectio. containing 5 mEq/ml should be added to the patients intravenous infusion?

I have one question :   Find the A and T% of a 6.5X10-4 Mol L-1 solution of a drug ( molecular weigth 200 ) whose absorpitvity is 0.026 L cm-1 g-1 at 520 nm when measured in a cell of 2.00 cm pathlength ?

3. Which of the following statements best describes a non-specific assay? directly measures the concentration of an analyte indirectly measures the concentration of an analyte O changes color as a function of analyte concentration measures the concentration of analyte using a absorption spectrometer

q41 IF YOU DO NOT KNOW THE ANSWER PLEASE DO NOT REJECT IT please calculate the unknown concentration of the protein D wih an absorbance value of A412 given the standard curve indicated in the table. write your answers in numbers only with 2 decimals. protein concentration (ug/ml) absorbance 0 0.000 0.02 0.161 0.04 0.284 0.06 0.438 0.08 0.572 0.10 0.762

EDTA is a hexaprotic system with the pK, values: "Ooc-CH2 HC-coo pKal = 0.00, pK2 = 1.50, pK3 = 2.00, pK4 = 2.69, N-CH,-CH,-N: pKas = 6.13, and pK6 = 10.37. "ooc-CH, H.c-coo %3D The distribution of the various protonated forms of EDTA EDTA- (or Y) will therefore vary with pH. For equilibrium calculations involving metal complexes with EDTA, it is convenient to calculate the fraction of EDTA that is in the completely unprotonated form, Y. This fraction is designated ayt- . Calculate ayt- at two pH values. pH = 3.85 pH = 10.70 aya =

Symbicort 80/4.5 is an oral inhalation product containing 80 mcg of budesonide and 4.5 mcg of formoterol fumarate per inhalations twice daily. how much of each drug would be administered daily? A) 0.32 mg budesonide , and 0.18 mg formoterol fumarate B) 320 mcg budesonide , and 0.18 mg formoterol fumarate C) 0.32 mg budesonide , and 0.018 mg formoterol fumarate D) 160 mcg budesonide , and 9 mcg formoterol fumarate

What are the visible results for these tests?