Carbachol causes contractions the isolated rat ileum to contract. The responses obtained to increasing concentrations of carbachol are tabulated below. Graph the data as log concentration versus % maximum response, using Excel or another spreadsheet program. Use the graph to estimate the EC50 value for carbachol and indicate its position on the graph. Conc (M) Exp 2 (% max response) Exp 1 Exp 3 (% max response) (% max response) 1.00E-09 3.00E-09 10 9. 20 1.00E-08 45 35 48 3.00E-08 57 69 72 1.00E-07 74 81 91 3.00E-07 95 85 96 1.00E-06 100 100 99 3.00E-06 100 98 99
Carbachol causes contractions the isolated rat ileum to contract. The responses obtained to increasing concentrations of carbachol are tabulated below. Graph the data as log concentration versus % maximum response, using Excel or another spreadsheet program. Use the graph to estimate the EC50 value for carbachol and indicate its position on the graph. Conc (M) Exp 2 (% max response) Exp 1 Exp 3 (% max response) (% max response) 1.00E-09 3.00E-09 10 9. 20 1.00E-08 45 35 48 3.00E-08 57 69 72 1.00E-07 74 81 91 3.00E-07 95 85 96 1.00E-06 100 100 99 3.00E-06 100 98 99
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Carbachol causes contractions the isolated rat ileum to contract. The responses obtained
to increasing concentrations of carbachol are tabulated below. Graph the data as log
concentration versus % maximum response, using Excel or another spreadsheet
program. Use the graph to estimate the EC50 value for carbachol and indicate its position
on the graph.
Conc (M)
Exp 1
Exp 2
Exp 3
(% max response)
(% max response)
(% max response)
1.00E-09
3.00E-09
10
20
1.00E-08
45
35
48
3.00E-08
57
69
72
1.00E-07
74
81
91
3.00E-07
95
85
96
1.00E-06
100
100
99
3.00E-06
100
98
99
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