Seeley's Anatomy & Physiology
11th Edition
ISBN: 9781259254963
Author: Jennifer Regan (author), Andrew Russo (author), Rod Seeley (author) Cinnamon Vanputte (author)
Publisher: McGraw Hill Higher Education
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Chapter 9.4, Problem 30AYP
Summary Introduction
To analyze:
The importance of acetylcholinesterase in the synaptic cleft.
Introduction:
The neurotransmitter is the molecule that allows the neurons to communicate with target and they require the presence of calcium ion for its release. The most common type of neurotransmitter is acetylcholine.
Acetylcholinesterase plays a key role in breaking down the acetylcholine present in the synaptic cleft to acetic acid and choline.
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Students have asked these similar questions
Which of the following statements about action potentials and information transmission in the synaptic cleft is FALSE?
1. Action potentials determine the amount of neurotransmitters that are released into the synaptic cleft
2.Action potentials ultimately result in more calcium leaving the target cell at the postsynaptic membrane
3. Action potentials determine the duration that neurotransmitters are released into the synaptic cleft
4. Action potentials ultimately result in more calcium entering the neuron at the axon terminal
Arrange the events that occur during synaptic transmission. Use letters A-F to denote the
correct sequence. Use the diagram on the right as a clue.
Example:
SENDING
NEURON
vescJes
B 1. lon channel opens
Synepto
SYNAPSE
1. lon channel opens
2. Neurotransmitter is released into synaptic
cleft
SYNAPTIC
CLEFT
RECEMNG
NEURC4
Neurotransmitter
To us
3. Vesicle fuses with plasma membrane
Jon chzn nels
Neurotrensmitter
Feptor
Neurotrensmitter broen
down zna selaesed
4. Neurotransmitter binds to receptor
tOnS
5. Action potential arrives
辦
6. lon channel closes
What do you mean by synaptic knobs?
Chapter 9 Solutions
Seeley's Anatomy & Physiology
Ch. 9.1 - List and describe the functions performed by...Ch. 9.1 - State the functions of smooth and cardiac muscle...Ch. 9.1 - Using table 9.1, distinguish among skeletal,...Ch. 9.2 - Identify the four specialized functional...Ch. 9.2 - Outline the differences in control and function...Ch. 9.3 - Name the connective tissue layers that surround...Ch. 9.3 - What are motor neurons? How do the axons of motor...Ch. 9.3 - What is the origin of muscle fibers? How do you...Ch. 9.3 - What are T tubules and the sarcoplasmic reticulum?Ch. 9.3 - Prob. 10AYP
Ch. 9.3 - Prob. 11AYPCh. 9.3 - Prob. 12AYPCh. 9.3 - Prob. 13AYPCh. 9.3 - Prob. 14AYPCh. 9.3 - Prob. 15AYPCh. 9.3 - Prob. 16AYPCh. 9.3 - Prob. 17AYPCh. 9.4 - What type of ion channel contributes to the...Ch. 9.4 - What are the two types of gated ion channels in...Ch. 9.4 - Prob. 20AYPCh. 9.4 - Prob. 21AYPCh. 9.4 - List the two types of voltage-gated channels the...Ch. 9.4 - Prob. 23AYPCh. 9.4 - Prob. 24AYPCh. 9.4 - Prob. 25AYPCh. 9.4 - Prob. 26AYPCh. 9.4 - Describe the structure of a neuromuscular...Ch. 9.4 - Prob. 28AYPCh. 9.4 - Prob. 29AYPCh. 9.4 - Prob. 30AYPCh. 9.4 - Prob. 31AYPCh. 9.4 - What ion is necessary for movement of the...Ch. 9.4 - Describe the steps in cross-bridge cycling. How is...Ch. 9.4 - Prob. 34AYPCh. 9.5 - List the phases of a muscle twitch, and describe...Ch. 9.5 - Prob. 36AYPCh. 9.5 - Prob. 37AYPCh. 9.5 - Prob. 38AYPCh. 9.5 - Prob. 39AYPCh. 9.5 - How does the lack of on unresponsive period in...Ch. 9.5 - Distinguish between active tension and passive...Ch. 9.5 - Prob. 42AYPCh. 9.5 - Prob. 43AYPCh. 9.5 - What is muscle tone, and how is it maintained?Ch. 9.6 - Contrast the structural and physiological...Ch. 9.6 - Prob. 46AYPCh. 9.6 - Prob. 47AYPCh. 9.6 - What factors contribute to increases in muscle...Ch. 9.6 - Prob. 49AYPCh. 9.6 - Prob. 50AYPCh. 9.7 - What is fatigue? List the three locations where...Ch. 9.7 - Prob. 52AYPCh. 9.7 - Prob. 53AYPCh. 9.7 - List the energy sources used to synthesize ATP for...Ch. 9.7 - Prob. 55AYPCh. 9.7 - Prob. 56AYPCh. 9.7 - Prob. 57AYPCh. 9.7 - Prob. 58AYPCh. 9.8 - Describe a typical smooth muscle cell. How do its...Ch. 9.8 - Prob. 60AYPCh. 9.8 - Prob. 61AYPCh. 9.8 - Compare visceral smooth muscle and multiunit...Ch. 9.8 - Prob. 63AYPCh. 9.8 - Prob. 64AYPCh. 9.8 - How are spontoneous contractions produced in...Ch. 9.8 - Prob. 66AYPCh. 9.8 - Prob. 67AYPCh. 9.8 - Prob. 68AYPCh. 9.9 - Prob. 69AYPCh. 9.9 - Prob. 70AYPCh. 9.10 - Prob. 71AYPCh. 9 - Which of these is true of skeletal muscle? a....Ch. 9 - Prob. 2RACCh. 9 - Prob. 3RACCh. 9 - Each myofibril Is made up of many muscle fibers....Ch. 9 - Prob. 5RACCh. 9 - Which of these statements about the molecular...Ch. 9 - Prob. 7RACCh. 9 - Prob. 8RACCh. 9 - Prob. 9RACCh. 9 - Prob. 10RACCh. 9 - Prob. 11RACCh. 9 - Prob. 12RACCh. 9 - Prob. 13RACCh. 9 - With stimuli of increasing strength, which of...Ch. 9 - Considering the force of contraction of a skeletal...Ch. 9 - Which of these events occurs during the lag...Ch. 9 - Prob. 17RACCh. 9 - Prob. 18RACCh. 9 - Given the conditions: (1) low ATP levels (2)...Ch. 9 - Prob. 20RACCh. 9 - Prob. 21RACCh. 9 - Prob. 22RACCh. 9 - Prob. 23RACCh. 9 - Prob. 24RACCh. 9 - Which of these statements concerning aging and...Ch. 9 - Prob. 1CTCh. 9 - A patient is thought to be suffering from either...Ch. 9 - Design an experiment to test the following...Ch. 9 - Explain what is happening at the level of...Ch. 9 - Predict the shape of an active tension curve for...Ch. 9 - Prob. 6CTCh. 9 - Prob. 7CTCh. 9 - Prob. 8CTCh. 9 - Prob. 9CTCh. 9 - Prob. 10CTCh. 9 - Prob. 11CTCh. 9 - Prob. 12CT
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Given the steps shown below, which of the following is the correct sequence for transmission at a chemical synapse? 1. neurotransmitter binds with receptor 2. sodium ions rush into neuron's cytoplasm 3. action potential depolarizes the presynaptic membrane 4. ion channel opens to allow particular ion to enter cell 5. synaptic vesicles release neurotransmitter into the synaptic cleft O 1, 2, 3, 4, 5 O 5, 1, 2, 4, 3 O 2, 3, 5, 4, 1 O4, 3, 1, 2, 5 O 3, 2, 5, 1, 4arrow_forwardHow can the levels of neurotransmitter in the synaptic cleft be regulated?arrow_forwardMuch of our current understanding of synapse development originated from studying the neuromuscular junction. What are the special features of the neuromuscular junction that make it a useful model system for synaptogenesis? As an example, describe a study that could not have been made in synapses in the central nervous system.arrow_forward
- What would happen to synaptic transmission if you blocked the degradation and/or reuptake of excitatory neurotransmitters in the synaptic cleft? What if the neurotransmitters were inhibitory?arrow_forwardPut the following events in chronological order. (Some of the steps may be missing.)1) Ca*+ floods into the pre-synaptic neuron.2) ch (Acetylcholine) binds to ACh receptors in the sarcolemma.3) Na+ floods into the post-synaptic muscle cell.4) The A.P arrives at the pre-synaptic terminal causing Ca+ channels to open.5) Ach from the synaptic vesicles spills into the pre-synaptic cleft.6) A post-synaptic action potential results in the muscle fiber (depolarizationarrow_forwardWhich types of patch clamp technique should be used if you want to determine if a particular compound is influencing synaptic transmission presynaptically or post synaptically?arrow_forward
- If action potential propagation from one neuron to another neuron requires ACh release, what event at the synaptic cleft explains the need for action potentials to arrive at a high rate before the post-synaptic membrane achieves threshold? the lack of sodium voltage gated channels on the post-synaptic membrane O the rapid breakdown of ACh by ACHE at the synaptic cleft the slow release of ACh by the synaptic vessicles the slow movement of sodium through chemical gates Previous Next MacBook Airarrow_forwardI have stimulated a neuron with dopamine for a second followed by treating it with cocaine and calcium chelating agent (which chelates out all calcium from the system making them unavailable for function), what will be the effect of such impulse on generating an action potential in the post-synaptic neuron? Will it be different if I pretreat the set of nerve cells with cocaine and calcium chelating agent followed by stimulating the neuron with dopamine? Justify your answer with proper reasoning in brief.arrow_forwardWhich of the following neuronal changes is associated with short term synaptic strength? O a. Changes in the size of neural spines o b. Changes in the shape of neural spines с. Increased production of neurotransmitter vesicles in the presynaptic cell o d. Increased buildup of Ca²+ in the terminal knob of the presynaptic axon О е. Increased expression of postsynaptic neurotransmitter receptorsarrow_forward
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