Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Textbook Question
Chapter 9, Problem 4P
Why is a type O individual considered a universal blood donor? Why is a type AB individual considered a universal acceptor?
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Why is a person with type AB blood able to receive a blood transfusion from a donor with any of the major blood types (A, B, AB, and O) but is able to donate blood only to another type AB individual?
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Your friend has type O blood and is being transfused with type AB blood. We would
ONo reaction because type O blopd is the unlyersal acceptor.
ONo reaction because type AB is the universal donor.
)A reaction, because type O blood has ant bodies to both the A and B antigens.
OA reaction, because type AB blood has antibodics to the O antigen.
)No reaction because type AB blood contains no antibodies.
Chapter 9 Solutions
Biochemistry: Concepts and Connections (2nd Edition)
Ch. 9 - Prob. 1PCh. 9 - -D-Galactopyranose rotates the plane of polarized...Ch. 9 - Provide an explanation for the fact that a-...Ch. 9 - Why is a type O individual considered a universal...Ch. 9 - The disaccharide , -trehalose differs from the ,...Ch. 9 - A reducing sugar will undergo the Fehling...Ch. 9 - Prob. 7PCh. 9 - Prob. 8PCh. 9 - Indicate whether the structures shown are R and S...Ch. 9 - Prob. 10P
Ch. 9 - Draw (using Haworth projections) the fragments of...Ch. 9 - One or more of the compounds shown below will...Ch. 9 - Why do you suppose that the influenza virus...Ch. 9 - Prob. 14PCh. 9 - Are mannose and galactose epimers? Allose and...Ch. 9 - Prob. 16PCh. 9 - Explain in about one sentence why it is important...Ch. 9 - Prob. 18PCh. 9 - Prob. 19PCh. 9 - Prob. 20PCh. 9 - Prob. 21PCh. 9 - Prob. 22PCh. 9 - Prob. 23P
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- Why is it important to match HLA alleles between donor and recipient in organ transplantation?arrow_forwardwhat is the role that B^s-phe85 and Bs-Leu88 play in sickle cell anemia. please give a shirt and direct answerarrow_forwardHow does capillary electrophoresis differ from gel electrophoresis? a) The capillary system can distinguish if an individual is heterozygous. b) The capillary system does not rely on DNA having a charge. c) The capillary system does not separate DNA fragments by their size. d) None of the abovearrow_forward
- Why is it important that cell surface markers be similar when transplanting donor tissue into a host? How do the alleles of the glycosyltransferase (GT) gene control the presence of A and B antigens on the surface of red blood cells?arrow_forwardWhat causes hemolytic disease of the newborn (erythroblastosis fetalis)? Why does the condition not arise in cases of ABO incompatibility?arrow_forwardEven though instances of fetal, maternal ABO, incompatibility are common, severe hemolytic disease due to ABO incompatibility is rare. Which of the following best explains this difference? A) ABO incompatibility causes extensive extra medullary hematopoiesis B) antibodies against ABO antigens do not bind complement C) the maternal immune system is tolerant to ABO ANTIGENS D) most anti- A or anti- B antibodies are of IgM type and do not cross the placenta E) the presence of concurrent Rh incompatibility decreases the immunogenicity of erythrocytesarrow_forward
- What is BCL11A and how is it related to hemoglobin?arrow_forwardIn terms of antigens and antibodies, explain why O- is considered a universal donor and why AB+ is considered a universal recipient. Even so, why can’t whole blood O- be donated to a person of type AB+ blood?arrow_forwardIf you were given numbers for FVC and FEV1 for several individuals, how would you determine which onewas most likely to suffer from a chronic obstructionary disease? Explain.arrow_forward
- On the battlefield, a medic is treating a soldier who has lost a great deal of blood. They are out of blood typing supplies so the medic, who is Type O negative, simply donates his own blood to the patient. Why could this work? (Why is Type O called the universal donor?)arrow_forwardThe group of disorders associated with single gene mutations affecting amino acid sequences in the alpha and beta globin genes are called Question 10 options: A) thalassemias B) hemoglobinopathies C) hemolytic anemias D) megaloblastic anemiasarrow_forwardDr. Martin said a donor with type B- could donate blood to an AB+ recipient. AB+ is a universal cell recipient but never a universal whole blood recipient. So, why does hemolysis result from B- whole blood transfused into an AB+ recipient?arrow_forward
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