Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 9, Problem 13P
Why do you suppose that the influenza virus protein that binds the virus to an infected cell is hemagglutinin? Hemagglutinin is the clumping together of red blood cells.
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Chapter 9 Solutions
Biochemistry: Concepts and Connections (2nd Edition)
Ch. 9 - Prob. 1PCh. 9 - -D-Galactopyranose rotates the plane of polarized...Ch. 9 - Provide an explanation for the fact that a-...Ch. 9 - Why is a type O individual considered a universal...Ch. 9 - The disaccharide , -trehalose differs from the ,...Ch. 9 - A reducing sugar will undergo the Fehling...Ch. 9 - Prob. 7PCh. 9 - Prob. 8PCh. 9 - Indicate whether the structures shown are R and S...Ch. 9 - Prob. 10P
Ch. 9 - Draw (using Haworth projections) the fragments of...Ch. 9 - One or more of the compounds shown below will...Ch. 9 - Why do you suppose that the influenza virus...Ch. 9 - Prob. 14PCh. 9 - Are mannose and galactose epimers? Allose and...Ch. 9 - Prob. 16PCh. 9 - Explain in about one sentence why it is important...Ch. 9 - Prob. 18PCh. 9 - Prob. 19PCh. 9 - Prob. 20PCh. 9 - Prob. 21PCh. 9 - Prob. 22PCh. 9 - Prob. 23P
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- Sickle cell anemia is a hereditary disease in which a faulty hemoglobin (Hb S) molecule is produced. A single DNA base change, from adenine to thymine, leads to the substitution of valine for glutamic acid leading to the production of hemoglobin S. Discuss the steps involved in the production of this molecule.arrow_forwardA virus has a double-stranded RNA genome that has 1800 base-pairs. Of these, 20 % are cytosine. How many uracil nucleotides would be present in this virus? Show all your calculations.arrow_forwardAdenine always pairs witharrow_forward
- Adenosine triphosphate is an imortant molecule becauseitarrow_forwardWhy are proteins synthesised from spirulina called single cell anemia?arrow_forwardWhen human hemoglobin undergoes a mutation, the mutant protein usually does not replace all of the normal HbA in the red blood cells or erythrocytes of the individual. The erythro- cytes contain mixtures of varying amounts of both HbA and the mutant protein depending on the mutation and the individual. Hb Yakima is a mutant human Hb with an Asp-(B99)His mutation. The diagram on the right shows that Hb Yakima was separated by DEAE-cellulose chromatography from HbA with a 0 – 0.1 M linear gradient of NaCl buffered to pH 8.3. Why is chromatog- raphy carried out at pH 8.3? If the isoelectric point of HbA is 6.85, what is the change in total charge caused by the mutation?How does the change in charge explain the chromatography elution profile of the Hb Yakima/HbA mixture? 1,5 -Hb-A Hb -Yakima 1.0 0.5- 20 40 60 80 00 Fraction number O.D578 nmarrow_forward
- Tenofovir, an analog of adenosine monophosphate, is a nucleoside reverse transcriptase inhibitor used to treat HIV infection. Atazanavir, also used to treat HIV infection, is a protease inhibitor. Approximately 1 in 1,000 virus particles carries a mutation that confers resistance against any given anti-HIV drug. If there are 1010 virus particles circulating in a patient, roughly how many of them would be resistant to both tenofovir and atazanavir? - 104 - 106 - 107 - 5 x 107 - 1010arrow_forwardOne of the causes of morbidity for the Zika Virus is Guillain-Barré Syndrome, an immune attack of nerve cells. One possible mechanism for this is the virus's interference with normal immune function. In HIV the virus uses the CD4 receptor to enter T-cells. To assess if this might be a possibility in Zika infections BLAST the CD4 Reference Sequence (NG 027688.1) against the Zika Virus (taxid:64320) choosing "blastn" under Program Selection (select all that apply): O None of the recovered sequences have identities of greater than 80%. O Multiple Zika virus isolates are observed to have E-values of less than 0.02. O High scoring BLAST hits are observed in Zika virus isolates from humans, mosquitoes, and monkeys. O The BLAST hits return a partial cds collected in Uganda in 1947 - isolate Uganda1947.arrow_forwardYou are preparing to give your patient 40mg of Furosemide. Furosemide comes packaged as 10mg/mL. How many mL of Adenosine should you administer?arrow_forward
- What will be the effect of the following changes to the protein structure of hemoglobin and its function? A. Replacement of the proximal histidine residue at the 8thposition of the F helix by asparagine. B. A phenylalanine to proline mutation resulting in decreased cooperativity of the polypeptide chains. C. Replacement of a nonpolar amino acid in the interior of the protein to a hydrophilic amino acid.arrow_forwarda) 5'-ATGGGCTCGCACTCATAA-3' b) 5'-ATGGTCTCGAACTCATAA-3' c) 5'-ATGGGCTCGAACTCATAA-3' d) 5'-ATGGGCTCGAACACATAA-3' e) 5'-ATGGGCTCGAATTCATAA-3' Excuse me, the answer you shows to me is not appear in the five options.arrow_forwardIn a [1] infection, the viral DNA is inserted into the host cells DNA. it remains there and is copied each time the cell multiplies.arrow_forward
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