BIOLOGY
5th Edition
ISBN: 9781265202859
Author: BROOKER
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Chapter 9, Problem 3TY
Summary Introduction
Introduction: Cell signaling involves many stepwise changes in the cell such as activation of receptor, signal transduction, and a response by the cell.
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All cells of a multicellular organism may not respond in the same wayto a particular ligand (signaling molecule) that binds to a cell surfacereceptor. The difference in response may be due toa. the type of receptor for the ligand that the cell expresses.b the affinity of the ligand for the receptor in a given cell type.c. the type of signal transduction pathways that the cell expresses.d. the type of target proteins that the cell expresses.e. all of the above.
Lipid-soluble signaling molecules, such as testosterone, cross the membrane of all cells but only affect target cells because
a.
intracellular receptors are only present in target cells
b.
only target cells possess the cytosolic enzymes that transduce the testosterone
c.
target cells are the only cells that can initiate the phosphorylation cascade leading to the transcription factor
d.
only target cells retain the appropriate DNA segments
Please choose one of these choices
A. Since protein A is embedded in the membrane., the mutation will be silent and not affect the cellular response.
B. The molecule that normally binds to protein A will not enter the cell, thus no cellular response will occur.
C. The molecule that normally binds to protein A will no longer attach, deactivating the cellular response.
D. Production if activated molecule 1 will stop, bht production of activated molecules 2 and 3 will continue.
Chapter 9 Solutions
BIOLOGY
Ch. 9.1 - Figure 9.1 Response of a yeast cell to glucose....Ch. 9.1 - Prob. 1CSCh. 9.1 - Which type of signal, paracrine or endocrine, is...Ch. 9.1 - Prob. 3CCCh. 9.2 - Prob. 1CSCh. 9.2 - Prob. 2CSCh. 9.2 - Prob. 1CCCh. 9.3 - Prob. 1CSCh. 9.3 - Prob. 1CCCh. 9.3 - Prob. 2CC
Ch. 9.3 - In the case of signaling pathways involving...Ch. 9.5 - Prob. 1EQCh. 9.5 - Prob. 2EQCh. 9.5 - Prob. 3EQCh. 9.5 - Prob. 1CCCh. 9 - Prob. 1TYCh. 9 - Prob. 2TYCh. 9 - Prob. 3TYCh. 9 - Prob. 4TYCh. 9 - Prob. 5TYCh. 9 - The relay protein Ras is part of the EGF pathway...Ch. 9 - Prob. 7TYCh. 9 - Prob. 8TYCh. 9 - Prob. 9TYCh. 9 - Prob. 10TYCh. 9 - Prob. 1CQCh. 9 - Conceptual Questions What are the three stages of...Ch. 9 - Prob. 3CQCh. 9 - Prob. 1COQCh. 9 - Prob. 2COQ
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- What type of cell signaling receptor is depicted below a. Cytoplasmic Receptor b. Transmembrane Receptor c. Intracellular Receptor d. Nuclear Receptorarrow_forwardHydrophobic signaling molecules act by a. binding to plasma proteins b. starting second messenger systems c. binding to receptors inside the cell d. starting action potentialsarrow_forwardEGF signals by binding to cell surface EGF receptors. Which of these observations, if true, would BEST explain EGF’s mechanism of action? A. EGF is hydrophilic and can easily diffuse through the cell membrane B. EGF is hydrophobic and can easily diffuse through the cell membrane C. EGF is hydrophilic and cannot diffuse through the cell membrane D. EGF is hydrophobic and cannot diffuse through the cell membranearrow_forward
- Which of the following elements may be in the transduction part of cell signaling? Select one: a. A phosphatase b. A kinase c. cyclin AMP d. ions e. All answers are correctarrow_forwardWhich of the following are methods of cellular signaling? Select one: a. All the answers are correct. b. Connections through fibers of the ECM from one cell to another c. Ligand binding to a receptor in the cell membrane d. Desmosomes ‘pulling’ one cell to another e. Lipid or gas ligand binding to an intracellular receptorarrow_forwardIn a clinical study, it was found that copaiba essential oil positively regulated multiple signaling pathways in neuronal cells. These included the following signaling pathways which regulate neuronal metabolism, proliferation and immunity: (Select all that apply.) Choose at least one answer. a. AMPK b. pI3K/Akt/mTOR c. MAPK d. JAK/STATarrow_forward
- During cell signaling, binding of a ligand to the outside of a cell leads to: A. A signal being sent inside the cell B. The ligand being transported into the cell C. A and B D. None of the abovearrow_forwardA cell has epinephrine receptors, yet is unable to respond to epinephrine signaling. One possible reason is: A. The cell has no DNA. B. The cell is missing a functional G-protein or adenylyl cyclase. C. All of the epinephrine receptors are on the cell’s surface. (They’re supposed to be in the cytoplasm!) D. Both A and C.arrow_forwardDefine the following terms: a. growth factors b. cytokine c. second messenger d. enzyme cascade e. desensitizationarrow_forward
- Hormones are chemical signaling molecules produced by specialized cells and transmitted via the circulatory system to all other cells in the body. Which of the following describes a condition that needs to be met for a target cell to re- ceive the signaling molecules? A B с D The size and shape of the target cell needs to be similar to that of the cell that secreted the hormone. The location of the target cell needs to be within the local region of the cell that secreted the hormone. The target cell needs to have sufficient ATP to transport the hormone into the cell. The cytosol of the target cell has to have receptors that recognize and bind the hormone.arrow_forwarda universal feature of cell signaling receptors is that they? a. undergo a structural (shape) change when the signal molecule is bound b. are present only in the plasma membrane c. are only ion channels d. are protein kinases e. aer only nuclear receptorsarrow_forwardWhich of the following exert their cell signaling ability by directly phosphorylating other proteins? multiple answers A. RAS B. Epidermal Growth factor C. HER2 D. SRC E. Estrogen Receptorarrow_forward
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