Concept explainers
Interpretation:
The starting material, which gives the desired product through the given defined reaction on working backward, is to be deduced.
Concept introduction:
Acid catalyzed dehydration is a reaction in which the alcohol is converted into
Elimination reaction: A reaction in which two substituent groups present on adjacent positions are detached and a double bond is formed.
Nucleophilic substitution reaction: A reaction, in which one of the hydrogens of a hydrocarbon, or a
A nucleophile is a molecule or atom with negative charge or a lone pair of electrons.
The reaction in which the halide group is removed through elimination reaction to form the alkene is called dehydrohalogenation.
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Organic Chemistry
- Predict the major product or the necessary reagent or reactant to complete each of the following reactions. In the box before each reaction, indicate the mechanism followed by the reaction. (Free radical (FR), SN2, SN1). (b) (a) Cl₂ CH₂CH₂OH (a) 1 hv 2 (b) H Br H₂O Na+ SCH3 (c) (d) CI "CH3arrow_forwardApply retrosynthetic analysis to guide the preparation of each of the following compounds from the indicated starting material, then write out the synthesis showing the necessary reagents. (a) 1-Propanol from 2-propanol (b) 1,2-Dibromopropane from 2-bromopropane (c) 1-Bromo-2-propanol from 2-propanol (d) 1-Bromo-2-methyl-2-propanol from tert-butyl bromide (e) 1,2-Epoxypropane from 2-propanol (f) tert-Butyl alcohol from isobutyl alcohol (g) tert-Butyl iodide from isobutyl iodide (h) trans-2-Chlorocyclohexanol from cyclohexyl chloridearrow_forward(a) Although phenoxide ion has more number of resonating structures than carboxylate ion, carboxylic acid is a stronger acid than phenol. Give two reasons.(b) How will you bring about the following converstions?(i) Propanone to propane (ii) Benzoyl chloride to benzaldehyde(iii) Ethanal to but-2-enalarrow_forward
- Starting with 2-methylpropene, outline a synthesis of (a) (CH3)3COH (b) (CH3)2C(OH)CH2Brarrow_forwardDraw the structural formula(s) for the major product(s) of each of the following reactions. Unless required, ignore stereochemical details.arrow_forward2B Suggest a short synthetic route for the preparation of compound D from compound C OH Br COOH C D Note: Apart from compound C, you can also use organic reagents with up to 1 C atom. The number of arrows in the figure above does not necessarily correspond to the number of steps.arrow_forward
- (c) Answer each of the questions below that relate to acetophenone: Xo (i) (ii) (iii) Draw the structure of the enol form of acetophenone. Give a stepwise mechanism for the conversion of acetophenone into its enol form. Show how each of the three compounds A, B and C below can be prepared from acetophenone. Explain clearly what reactants/reagents would be required in each case. odocor A B Br Carrow_forwardProvide the necessary reagents to accomplish the desired organic reactions. Please number the steps and note that some reactions will require more than one step. (a) (b) Me Br OMe NH Me ÓTs OMearrow_forwardDraw a structural formula for the alcohol formed by treating each alkene with borane in tetrahydrofuran (THF) followed by hydrogen peroxide in aqueous sodium hydroxide, and specify stereochemistry where appropriate. (a) (d) (b) (e) (c)arrow_forward
- Show, by writing an appropriate series of equations, how you could prepare propyne from each of the following compounds as starting materials. You may use any necessary organic or inorganic reagents. (a) 2-Propanol (d) 1,1-Dichloroethane (b) 1-Propanol (e) Ethyl alcohol (c) Isopropyl bromidearrow_forward(d) How would you prepare any one of the following compounds from benzene? More than one step may be involved in each case. (a) (b) OH Br m-Bromo benzoic acid Phenyl acetic acidarrow_forwardGuiding your reasoning by retrosynthetic analysis, show how you could prepare each of the following compounds from the given starting material and any necessary organic or inorganic reagents. All require more than one synthetic step. (a) Cyclopentyl iodide from cyclopentane (b) 1-Bromo-2-methylpropane from 2-bromo-2-methylpropane (c) meso-2,3-Dibromobutane from 2-butyne (d) 1-Heptene from 1-bromopentane (e) cis-2-Hexene from 1,2-dibromopentane (f) Butyl methyl ether (CH3CH2CH2CH2OCH3) from 1-butenearrow_forward
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