Bundle: Chemistry for Today: General, Organic, and Biochemistry, Loose-Leaf Version, 9th + LMS Integrated OWLv2, 4 terms (24 months) Printed Access Card
9th Edition
ISBN: 9781337598255
Author: Spencer L. Seager
Publisher: Cengage Learning
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Chapter 7, Problem 7.83E
Suppose you have a bag made of a membrane like that in Figure
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Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
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Chapter 7 Solutions
Bundle: Chemistry for Today: General, Organic, and Biochemistry, Loose-Leaf Version, 9th + LMS Integrated OWLv2, 4 terms (24 months) Printed Access Card
Ch. 7 - Many solutions are found in the home. Some are...Ch. 7 - Prob. 7.2ECh. 7 - Classify the following as being a solution or not...Ch. 7 - Classify the following as being a solution or not...Ch. 7 - Use the term soluble, insoluble, or immiscible to...Ch. 7 - Use the term soluble, insoluble, or immiscible to...Ch. 7 - Define the term miscible. It is not defined in the...Ch. 7 - Classify the following solutions as unsaturated,...Ch. 7 - Prob. 7.9ECh. 7 - Prob. 7.10E
Ch. 7 - Prob. 7.11ECh. 7 - Classify each of the following solutes into the...Ch. 7 - Prob. 7.13ECh. 7 - Prob. 7.14ECh. 7 - Prob. 7.15ECh. 7 - Prob. 7.16ECh. 7 - Prob. 7.17ECh. 7 - Prob. 7.18ECh. 7 - Prob. 7.19ECh. 7 - Prob. 7.20ECh. 7 - Prob. 7.21ECh. 7 - Prob. 7.22ECh. 7 - Calculate the molarity of the following solutions:...Ch. 7 - Prob. 7.24ECh. 7 - Prob. 7.25ECh. 7 - Calculate: a. How many grams of solid would be...Ch. 7 - Prob. 7.27ECh. 7 - Prob. 7.28ECh. 7 - Calculate the concentration in (w/w) of the...Ch. 7 - Calculate the concentration in (w/w) of the...Ch. 7 - Prob. 7.31ECh. 7 - Calculate the concentration in (w/w) of the...Ch. 7 - Prob. 7.33ECh. 7 - Calculate the concentration in (v/v) of the...Ch. 7 - Calculate the concentration in (v/v) of the...Ch. 7 - Consider the blood volume of an adult to be 5.0L....Ch. 7 - Prob. 7.37ECh. 7 - Calculate the concentration in (w/v) of the...Ch. 7 - Calculate the concentration in (w/v) of the...Ch. 7 - Prob. 7.40ECh. 7 - Prob. 7.41ECh. 7 - Prob. 7.42ECh. 7 - Explain how you would prepare the following...Ch. 7 - Prob. 7.44ECh. 7 - Prob. 7.45ECh. 7 - Calculate the following: a. The number of grams of...Ch. 7 - Prob. 7.47ECh. 7 - Explain how you would prepare the following dilute...Ch. 7 - Prob. 7.49ECh. 7 - Prob. 7.50ECh. 7 - Prob. 7.51ECh. 7 - How many grams of solid Na2CO3 will react with...Ch. 7 - Prob. 7.53ECh. 7 - Prob. 7.54ECh. 7 - Prob. 7.55ECh. 7 - Prob. 7.56ECh. 7 - How many milliliters of 0.124MNaOH solution will...Ch. 7 - How many milliliters of 0.124MNaOH solution will...Ch. 7 - How many milliliters of 0.115MNaOH solution will...Ch. 7 - Stomach acid is essentially 0.10MHCl. An active...Ch. 7 - Prob. 7.61ECh. 7 - Prob. 7.62ECh. 7 - Prob. 7.63ECh. 7 - Calculate the boiling and freezing points of water...Ch. 7 - Calculate the boiling and freezing points of water...Ch. 7 - Prob. 7.66ECh. 7 - Prob. 7.67ECh. 7 - Prob. 7.68ECh. 7 - Calculate the osmolarity for the following...Ch. 7 - Prob. 7.70ECh. 7 - Calculate the osmotic pressure of a 0.125M...Ch. 7 - Prob. 7.72ECh. 7 - Prob. 7.73ECh. 7 - Calculate the osmotic pressure of a solution that...Ch. 7 - Prob. 7.75ECh. 7 - Prob. 7.77ECh. 7 - Prob. 7.78ECh. 7 - Prob. 7.79ECh. 7 - Suppose an osmotic membrane separates a 5.00 sugar...Ch. 7 - Prob. 7.81ECh. 7 - Prob. 7.82ECh. 7 - Suppose you have a bag made of a membrane like...Ch. 7 - Prob. 7.84ECh. 7 - Prob. 7.85ECh. 7 - Prob. 7.86ECh. 7 - Prob. 7.87ECh. 7 - Prob. 7.88ECh. 7 - Prob. 7.89ECh. 7 - When a patient has blood cleansed by hemodialysis,...Ch. 7 - Prob. 7.91ECh. 7 - Prob. 7.92ECh. 7 - Prob. 7.93ECh. 7 - Prob. 7.94ECh. 7 - Prob. 7.95ECh. 7 - Strips of fresh meat can be preserved by drying....Ch. 7 - If a salt is added to water, which of the...Ch. 7 - Prob. 7.98ECh. 7 - Prob. 7.99ECh. 7 - Prob. 7.100ECh. 7 - Which one of the following compounds is a...Ch. 7 - Prob. 7.102ECh. 7 - Prob. 7.103ECh. 7 - Prob. 7.104ECh. 7 - Prob. 7.105ECh. 7 - Prob. 7.106ECh. 7 - Prob. 7.107ECh. 7 - Prob. 7.108ECh. 7 - Prob. 7.109ECh. 7 - Prob. 7.110ECh. 7 - In a dilute solution of sodium chloride in water,...Ch. 7 - A salt solution has a molarity of 1.5M. How many...Ch. 7 - Prob. 7.113ECh. 7 - Prob. 7.114ECh. 7 - Prob. 7.115ECh. 7 - Prob. 7.116ECh. 7 - Prob. 7.117ECh. 7 - Prob. 7.118ECh. 7 - Prob. 7.119ECh. 7 - Prob. 7.120ECh. 7 - Prob. 7.121ECh. 7 - Prob. 7.122E
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Solutions: Crash Course Chemistry #27; Author: Crash Course;https://www.youtube.com/watch?v=9h2f1Bjr0p4;License: Standard YouTube License, CC-BY