Biochemistry
9th Edition
ISBN: 9781305961135
Author: Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher: Cengage Learning
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Chapter 7, Problem 67RE
Interpretation Introduction
Interpretation:
“Fighting Alzheimer’s disease by boosting the stability of the retromer is based on the hypothesis that most of the APP is cleaved in the endosome to release β amyloid”. Whether most of the APPs are cleaved on the cell membrane or not (as previously thought) is to be discussed.
Concept Information:
A neurodegenerative disease that has been mainly seen in old people that causes symptoms such as loss of memory, delusions and even changes in personality is known as Alzheimer’s disease. The brains of the individuals suffering from it shrink and also lose certain folds of the lobes.
A retromer is the complex used for shuttling proteins from the endosomes to the Golgi apparatus inside a cell.
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Chapter 7 Solutions
Biochemistry
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