The proposed role of a retromer in Alzheimer’s disease is to be discussed. Concept Information: A retromer is the complex used for shuttling proteins from the endosomes to the Golgi apparatus inside a cell. A neurodegenerative disease that has been mainly seen in old people that causes symptoms such as loss of memory, delusions and even changes in personality is known as Alzheimer’s disease. The brains of the individuals suffering from it shrink and also lose certain folds of the lobes.

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Reflect and Connect Choose one of the next two questions to answer: You can respond in the best format that reflects your answer. This can be in written form, graphical form, or perhaps in an audio form such as a podcast. Consider whether your response needs to be edited. Option 1 When you saw the person across the room that you wanted to meet, you walked over to introduce yourself. Your breathing rate and your heart rate increased with the level of your nervousness. After you calmed down, your systems returned to a balanced state. You should now be able to outline the parts of the nervous system and outline how they controlled these changes. Option 2 In the case of a survivor of a motor-vehicle accident who may be aware of pain in her legs but cannot move her legs, what part of the communications pathway was damaged? Justify your selection by explaining your choice. Include why you think each part of the communications pathway was or was not damaged.

Answer 1

Question

Chapter 7, Problem 66RE

Interpretation Introduction

Interpretation:

The proposed role of a retromer in Alzheimer’s disease is to be discussed.

Concept Information:

A retromer is the complex used for shuttling proteins from the endosomes to the Golgi apparatus inside a cell.

A neurodegenerative disease that has been mainly seen in old people that causes symptoms such as loss of memory, delusions and even changes in personality is known as Alzheimer’s disease. The brains of the individuals suffering from it shrink and also lose certain folds of the lobes.

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Reflect and Connect Choose one of the next two questions to answer: You can respond in the best format that reflects your answer. This can be in written form, graphical form, or perhaps in an audio form such as a podcast. Consider whether your response needs to be edited. Option 1 When you saw the person across the room that you wanted to meet, you walked over to introduce yourself. Your breathing rate and your heart rate increased with the level of your nervousness. After you calmed down, your systems returned to a balanced state. You should now be able to outline the parts of the nervous system and outline how they controlled these changes. Option 2 In the case of a survivor of a motor-vehicle accident who may be aware of pain in her legs but cannot move her legs, what part of the communications pathway was damaged? Justify your selection by explaining your choice. Include why you think each part of the communications pathway was or was not damaged.

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