Concept explainers
To determine: The reason due to which pattern baldness is more common in males than in females even though the gene resides on an autosome.
Introduction: There are obvious
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Chapter 7 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
- Male-limited precocious puberty results from a rare, sex-limited autosomal allele (P) that is dominant over the allele for normal puberty (p) and is expressed only in males. Bill undergoes precocious puberty, but his brother Jack and his sister Beth underwent puberty at the usual time, between the ages of 10 and 14. Although Bill's mother and father underwent normal puberty, his two maternal uncles (his mother's brothers) underwent precocious puberty. All of Bill's grandparents underwent normal puberty. Match the most likely genotypes for each relative in his family. If there is an equal likelihood of multiple genotypes for a relative, place each possible genotype. Relative Genotype Answer Bank Bill Pp PP PP Bill's brother Jack Bill's sister Beth Bill's father Bill's mother Bill's uncle Bill's grandfather Bill's grandmotherarrow_forwardX-linked lissencephaly is an X-link dominant trait pertaining to a brain disorder. It superficially resembles an autosomal dominant trait because both the daughters and sons of an affected female parent can be affected. Mr. Panganiban is affected by the said disorder while his wife is not. Using your knowledge in predicting the genetic possibilities of the offspring, what do you think would happen to their sons and daughters in the first filial generation? Females affected by an X-link dominant have 50% for their sons and daughters to be affected. Father affected by the X-linked dominant trait can transmit the trait to all his daughters. Males with lissencephaly could transmit the genetic disorder for both sons and daughters. Lissencephaly is an X-link limited dominant trait. It usually affects males because they have only a single chromosome.arrow_forwardFaulty Tooth Enamel Formation Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is notexpressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental…arrow_forward
- Pompe disease is a glycogen storage disorder caused by a lack of ⍺-glucosidase, the enzyme that converts glycogen to glucose in the muscles. Babies born with this disorder die by the age of two. Pompe disease is a genetic disorder caused by the presence of two recessive autosomal alleles. A man and a woman heterozygous for the condition have two female unaffected children. Determine the probability, expressed as a whole number percentage, of a third baby being born a male with Pompe disease. Your answer must include the use of a Punnett square as well as a legend indicating the allele symbols used. (2 marks)arrow_forwardKnowing that wrong number of chromosomes has serious, usually lethal consequences, briefly describe the most common inherited abnormalities in case of trisomy 21 and trisomy 13.arrow_forwardDuring the formation of a Barr body, histone H3 is methylated by PCR2 (polycomb repressive complex 2). True False 2. In an individual with complete androgen insensitivity syndrome, the Wolffian ducts degenerate but the Mullerian ducts persist and differentiate into adult structures. True Falsearrow_forward
- A highly talented 22-year-old female college athlete has just qualified to compete in the Summer Olympics. However, when she is required to undergo laboratory testing to measure testosterone levels, she is informed that she will not be permitted to compete because her testosterone levels are “too high for a female athlete”. Further medical and genetic testing reveal that she has a condition known as Complete Androgen Insensitivity Syndrome. She promptly hires an attorney to appeal the decision. A. What is the chromosomal sex of this female athlete? B. If she were subjected to a cytological test for the presence of a Barr body or bodies, what would typically be found on such a test performed on an individual having this condition? Please EXPLAIN why this is the case.arrow_forwardPompe disease is a glycogen storage disorder caused by a lack of a-glucosidase, the enzyme that converts glycogen to glucose in the muscles. Babies born with this disorder die by the age of two. Pompe disease is a genetic disorder caused by the presence of two recessive autosomal alleles. A man and a woman heterozygous for the condition have two female unaffected children. Determine the probability, expressed as a whole number percentage, of a third baby being born a male with Pompe disease. Your answer must include the use of a Punnett square as well as a legend indicating the allele symbols used.arrow_forwardExplain the difference between X-linked recessive traits and X-linked dominant traits. What are the possibilities that a female child will be affected and express each of the traits?arrow_forward
- Amelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is not expressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental cross, and identify the…arrow_forwardAmelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is notexpressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental cross, and identify the possible…arrow_forwardAmelogenesis imperfecta (AI) is a disorder of faulty tooth enamel formation. It is inherited in an autosomal dominant and X-linked dominant pattern. The expression of AI disorder is determined by mutations in the autosomal alleles. One copy of the mutated allele (A) will cause the disorder. The severity of the disorder is determined by mutations in a gene carried on the X chromosome. Normal (or non-severe) abnormality (XN) is dominant over the abnormality (or severe) (Xn) allele. In the absence of the autosomal dominant allele, the abnormality gene on the X chromosome is not expressed. Question:A woman with normal teeth had four children with a man with non-severe form of AI: A boy was born without amelogenesis imperfecta A girl was born without amelogenesis imperfecta A boy was born with severe amelogenesis imperfecta A boy was born with non severe amelogenesis imperfecta Identify the parental genotypes. Complete the Punnett square for the parental cross, and identify the…arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning