Chapter 7.6, Problem 1EG

Summary Introduction

To determine: Whether XY individuals with complete androgen insensitivity (CAIS) have an unfair advantage in competing with XX individuals in athletics or not.

Introduction: A disorder where the pathway from genetic sex to phenotypic sex is disrupted is known as complete androgen insensitivity. In this, a mutation in a gene called androgen receptor which is present on the X chromosome is observed. This mutation causes XY individuals to depict phenotypic characteristics of females because the fetal body of these individuals does not react to the male sex hormone called androgen which is responsible for developing male phenotypic characteristics.