Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 7, Problem 12QP
Mutations Can Uncouple chromosomal Sex from
Discuss whether the following individuals (1) have male or female gonads, (2) are phenotypically male or female (discuss Wolffian/Müllerian ducts and external genitalia), and (3) are sterile or fertile.
- a. XY, homozygous for a recessive mutation in the testosterone biosynthetic pathway, producing no testosterone
- b. XX, heterozygous for a dominant mutation in the testosterone biosynthetic pathway, which causes continuous production of testosterone
- c. XY, heterozygous for a recessive mutation in the MIH gene
- d. XY, homozygous fora recessive mutation in the SRY gene that abolishes function
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
A. Deletion of the SOX9 gene leads to sex reversal resulting in a person with karyotype 46XY being phenotypically Explain the genetic basis for this.
B. Describe what would happen to the phenotype of a male with a mutation in the gene encoding SF1? Explain your answer.
Question 15: Consider the consequence if one of the mutations you tested for complementation
was a dominant mutation. You should see that complementation tests could not be used to provide
information about dominant mutations.
a) If a mutation were dominant how would your interpretation of the phenotype of the diploid be
altered?
No change would occur v
b) How would you test whether any of these trp mutations were dominant?
There is no way to test fc V
Explain this to me…..
Chapter 7 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 7.6 - Prob. 1EGCh. 7.6 - Prob. 2EGCh. 7 - As outlined in this chapter, sex can be defined at...Ch. 7 - As outlined in this chapter, sex can be defined at...Ch. 7 - Prob. 1QPCh. 7 - The Human Reproductive System Discuss and compare...Ch. 7 - Prob. 3QPCh. 7 - A Survey of Human Development from Fertilization...Ch. 7 - Prob. 5QPCh. 7 - Prob. 6QP
Ch. 7 - Prob. 7QPCh. 7 - How Is Sex Determined? The absence of a Y...Ch. 7 - Prob. 9QPCh. 7 - Mutations Can Uncouple Chromosomal Sex from...Ch. 7 - Prob. 11QPCh. 7 - Mutations Can Uncouple chromosomal Sex from...Ch. 7 - Prob. 13QPCh. 7 - Sex-Influenced and Sex-Limited Traits What method...Ch. 7 - Prob. 15QPCh. 7 - Prob. 16QPCh. 7 - Equalizing the Expression of X Chromosome Genes in...Ch. 7 - Equalizing the Expression of X Chromosome Genes in...Ch. 7 - Equalizing the Expression of X Chromosome Genes in...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The maternal-effect mutation bicoid (bcd) is recessive. Inthe absence of the bicoid protein product, embryogenesis isnot completed. Consider a cross between a female heterozygousfor the bicoid mutation (bcd+/ bcd-) and a homozygousmale(bcd-/ bcd-). How is it possible for a male homozygous for the mutationto exist?arrow_forwardQuestion:- A) Give one domain.motif found in the SRY portion and state clearly how it leads to the development of the Wollfian system. B) Explain the genotype and the phenotype of an XY female and how such an individual could occur. C) Explain the genotype and the phenotype of an XX male and how such an individual could occur.arrow_forwardCan I get an explanation for 1a, 1d, 1e, 2c, 2d and the calculations for the level of interference please.arrow_forward
- I would appreciate some help with this pedigree chart questionsarrow_forwardPlease help with the following question:arrow_forwardXX individuals can be sex-reversed males if one of their X chromosomes contains a translocated portion of the Y chromosome that includes the SRY gene. In light of what you now know about X-chromosome inactivation, it seems that this karyotype might have more complex consequences. In fact, although most such males are completely sex-reversed, X-chromosome inactivation can cause some of these XX males to have varying degrees of residual female characteristics. a. X-chromosome inactivation in normal XX embryos occurs earlier in development than SRY production in normal XY embryos. When present on a translocation X chromosome, SRY is subject to inactivation. Formulate a hypothesis to explain why many XX individuals with a translocation X chromosome that includes the SRY gene are not completely sex-reversed (male). b. Based on your answer to part (a), why do you think some individuals with this karyotype are completely sex-reversed?arrow_forward
- I need help pleasearrow_forwardYou are to discover the chromosomal location (autosomal or X linked) and mode of inheritance for two new fly mutations coughrotato (cp) and happyhour, (bb) The homozygous couchpotato (cpcp) phenotype is (sedentary) an extreme lack of activity The homozygous happyhour (hhhh) can drink any other fly under the table so phenotype (drinker) PARENTS Cross Male double homozygous mutants cp hh with Female wild wild CP HH are to be crossed BUT FIRST you don't know if either gene is on the X chromosome Parental diploid genotypes could be: male çpcphbbh female CPCPHHHH if Both genes autosomal or Male XcpYhbhh female XCPXCPHHHH if cp on the X chromosome and bh autosomal or Male cpcpXhhY female CPCPXHHXHH if hh on the X chromosome and cp autosomal What are the female and male PARENTAL GAMETE GENOTYPES for the above parental crosses if: a) Both genes were autosomal ((REMEMBER BOTH GENDER HAVE ONE GAMETE GENO) b) cp gene on the X chromosome and hh autosomal (REMEMBER MALES WITH HAVE 2 GAMETE GENO) c)…arrow_forwardHemophilia A is caused by a sex-linked recessive gene in human and in dogs. a. What proportions (and sexes), among their offspring will be hemophiliacs if a hemophilic male is mated to a homozygous nonhemophilic female?b. If a daughter produced by the mating in (a) is mated to a normal male, what proportions and (sexes) will be hemophilic among their offspring?arrow_forward
- B4. In a woman with translocation of a small chromosomal segment from the chromosome 5 on chromosome 10 and a normal phenotype, prenatal screening is done for the carrying fetus. The woman is 10 weeks pregnant. It is determined that the fetus will have a structural chromosomal abnormality (deficiency) and will manifest mental retardation. A. Detail the procedures followed by the clinician geneticist in order to arrive at the above diagnosis. In which comments supported? B. What is the name of the syndrome that the child will manifest? B3. In different strains of the bacterium E.coli an inability to copied. The following problems were recorded: Strain 1 : Copy not starting. Stem 2 : No primary segment is composed. Strain 3 : Many short DNA segments complementary and antiparallel with parent chains. Strain 4: Many errors in the newly synthesized chains. Indicate regions of the corresponding genome of bacterial strains that may have been mutated with resulting in the above…arrow_forwardPART 3– Sex Linkage Hemophilia is a recessive sex-linked disorder in which an important clotting factor protein (Factor VIII) is not produced in a functional form. Queen Victoria was a carrier of the recessive Factor VIII allele, meaning she carried the allele but was asymptomatic. Recently, historians have discovered that she secretly had an affair with the Austrian Count Chocula, who, unbeknownst to her, was a hemophiliac. Naturally, the Royal Family fought to have this information suppressed, but it was revealed that they had many children together. 1. Using the correct allele notation, write the genotypes for Queen Victoria and Count Chocula. 2. In the Punnett Square below, show the cross between the Queen and the Count. P> PĮarrow_forwardA woman is affected with Prader-Willi syndrome due to a deletion that includes both the Angelman syndrome and Prader-Willi syndrome genes. Although rare, fertility among Prader-Willi syndrome individuals has been documented. For each of the following, state what is the probability of the outcome if she were to become pregnant. Assume the male partner in the pregnancy has no genetic disorder. A) a child with neither Prader-Willi syndrome or Angelman syndrome B) A child with AS C) A child with Prader-Willi syndromearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Biology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Biology Today and Tomorrow without Physiology (Mi...
Biology
ISBN:9781305117396
Author:Cecie Starr, Christine Evers, Lisa Starr
Publisher:Cengage Learning
Great Glands - Your Endocrine System: CrashCourse Biology #33; Author: CrashCourse;https://www.youtube.com/watch?v=WVrlHH14q3o;License: Standard Youtube License