Biology (MindTap Course List)
Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 6, Problem 5TYU
Summary Introduction

Concept introduction: Receptors are large protein or glycoproteins that bind with the signaling molecule (ligand). The cells undergo receptor-ligand alterations and initiate the biological response. The ligand molecule binds with the cell surface receptors. G-protein-linked receptor may be monomeric or oligomeric. It belongs to a family of transmembrane proteins that loop back and forth through the plasma membrane for seven times.

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G protein–linked receptors (a) inactivate G proteins (b) activate first messengers (c) consist of 18 transmembrane alpha helices (d) have a tail that extends into the cytosol with a binding site for a G protein (e) are located in the cytoplasm or nucleus
Scaffold proteins (a) release kinases and phosphatases into the extracellular fluid (b) bind G proteins to cell membranes (c) increase accuracy but slow signaling cascades (d) organize groups of intracellular signaling moleculesinto signaling complexes (e) are transcription factors found mainly in plant cells
When a signaling molecule binds with a receptor, (a) G proteins are inactivated (b) a third messenger is activated (c) cell signaling is terminated (d) cAMP is produced by the receptor (e) the receptor becomes activated
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Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license