Prescott's Microbiology
10th Edition
ISBN: 9781259281594
Author: Joanne Willey, Linda Sherwood Adjunt Professor Lecturer, Christopher J. Woolverton Professor
Publisher: McGraw-Hill Education
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Chapter 6, Problem 4CHI
Chronic wasting disease (CWD) is a neurodegenerative disease of cervid animals (e.g., deer, elk, moose) caused by prions. Unlike other prion diseases, CWD is readily transmitted from one animal to another in a herd. How this occurs in not understood. However, evidence suggests the mode of transmission is by animal excreta: saliva, urine, and feces. In this mechanism, a healthy animal would be exposed to the prion present in excreta from a diseased animal. Since many cervids congregate, the prion would easily spread from one animal to another. One problem facing scientists studying CWD is measuring the amount of infectious prions in excreta and determining their source (i.e., whether they are produced solely in nervous system tissue or in organs of excretion). Why is CWD of concern to fish and wildlife biologists and game managers in states where CWD is prevalent (e.g., Colorado, Wyoming, Wisconsin)? Why would the presence of CWD prions in tissues other than those of the central nervous system be important to know? (Hint: Learn about the variant Creutzfeldt-Jakob epidemic that occurred in the 1990s.)
Read the original article: Haley, N. J., et al. 2011. Detection of chronic wasting disease prions in salivary, urinary, and intestinal tissues of deer: potential mechanisms of prion shedding and transmission. J. Virol. 85:6309.
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Chapter 6 Solutions
Prescott's Microbiology
Ch. 6.2 - MICRO INQUIRY Which capsids are icosahedral? Which...Ch. 6.2 - MICRO INQUIRY Are the capsomers at the vertices of...Ch. 6.2 - MICRO INQUIRY Why is T4 said to have binal...Ch. 6.2 - Retrieve, Infer, Apply 1. How are viruses similar...Ch. 6.2 - Retrieve, Infer, Apply 2. What is the difference...Ch. 6.2 - Retrieve, Infer, Apply 3. Compare the structure of...Ch. 6.2 - Retrieve, Infer, Apply 4. What is an envelope?...Ch. 6.2 - Retrieve, Infer, Apply 5. All four nucleic acid...Ch. 6.2 - Retrieve, Infer, Apply 6. The RNA genomes of some...Ch. 6.3 - MICRO INQUIRY Which of these mechanisms involves...
Ch. 6.3 - MICRO INQUIRY Why do the empty capsids remain...Ch. 6.3 - Explain why the receptors that viruses have...Ch. 6.3 - What probably plays the most important role in...Ch. 6.3 - How do you think the complexity of the viral...Ch. 6.3 - In general, DNA viruses can be much more dependent...Ch. 6.3 - Consider the origin of viral envelopes and suggest...Ch. 6.3 - Why are the proteins involved in virion assembly...Ch. 6.4 - Why is a lysogen considered a new or different...Ch. 6.4 - Define the terms lysogeny, temperate phage,...Ch. 6.4 - What advantages might a phage gain by being...Ch. 6.4 - Describe lysogenic conversion and its...Ch. 6.4 - How does a latent infection differ from a chronic...Ch. 6.4 - What is a cytocidal infection? What is a...Ch. 6.4 - Define the following terms: tumor, neoplasia,...Ch. 6.4 - Distinguish the mechanism by which dsDNA viruses...Ch. 6.5 - Prob. 1MICh. 6.5 - Prob. 1RIACh. 6.5 - Given that viruses must be cultivated to make...Ch. 6.7 - What are viroids and why are they of great...Ch. 6.7 - How does a viroid differ from a virus? From a...Ch. 6.7 - What is a prion? In what way does a prion differ...Ch. 6.7 - Prob. 4RIACh. 6 - Many classification schemes are used to identify...Ch. 6 - The origin and evolution of viruses is...Ch. 6 - Consider the separate stages of an animal virus...Ch. 6 - Chronic wasting disease (CWD) is a...Ch. 6 - Syn5 is a virus that infects photosynthetic...
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