Biological Science
5th Edition
ISBN: 9780321743671
Author: Scott Freeman
Publisher: PEARSON
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Chapter 49, Problem 8TYU
Summary Introduction
To review:
The binding of a hormone to more than one type of receptor is important.
Introduction:
The hormones are the chemical substances released by the endocrine glands into the bloodstream. They are specific in their action and bind to their specific receptors on or within the target cell only. They play a major role in growth, development, and maintenance of the body of a living organism.
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Why is the fact that a monomeric hormone binds simultaneously to two identical receptor molecules, thus promoting the formation of a dimer of the receptor, considered remarkable?
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Why is it regarded extraordinary that a monomeric hormone may attach to two identical receptor molecules simultaneously, hence stimulating the creation of a dimer of the receptor?
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- What general features make a chemical compound a hormone, and how do hormones achieve specificity for certain kinds of target cell?arrow_forwardWhy is knowing the KD of a hormone / receptor complex important?arrow_forwardWhat is the difference between a G protein and a receptor tyrosine kinase? Give an example of a hormone that uses each.arrow_forward
- If a hormone interacts with a membrane-bound receptor, then the cell’s DNA will be stimulated to synthesize and secrete a protein. True or False?arrow_forwardWhere in the cell would you expect to find an activated, ligand-bound steroid hormone receptor?arrow_forwardwhich of the following statements best characterizes the hormone-receptor interaction? a. receptors can have different affinities for multiple ligands b. each hormone will only interact with one type of receptor c. the hormone-receptor contact is generally irreversible d. most cells express receptors for all hormonearrow_forward
- How does the receptor location differ for lipid- versus water-soluble hormones and why?arrow_forwardHormones are signaling molecules that can alter cellular activity and gene expression. Hormones also have diverse chemical structures. How does the chemical nature of different classes of hormones influence how/where it interacts with target cells?arrow_forwardWhat characteristics of a hormone receptor make itspecific for one type of hormone?arrow_forward
- What cellular response (up-regulation or down-regulation) would you predict occurs in response to high doses of a drug that binds to a specific hormone receptor? Will more or less of the drug be required for the same response over time? Explain.arrow_forwardWhich of the following observations can be explained by the properties of hormone receptors? a) A certain tissue can react to more than one hormone b) A certain hormone affects only a specific tissue, not all tissues c) Some tissues react very quickly to a certain hormone, other tissues take many hours to react to the same hormonearrow_forwardWhat is the specific role of the protein kinase enzymes in the signal transduction pathway initiated by water-soluble hormones?arrow_forward
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