ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
10th Edition
ISBN: 9781260028355
Author: Carey
Publisher: MCG CUSTOM
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Chapter 4.7, Problem 10P
Interpretation Introduction

Interpretation:

The absolute configuration (R) or (S) in each of the given compound represented by the Fischer projections is to be determined.

Concept introduction:

A chirality center is the tetrahedral carbon which is directly attached to four different atoms or groups.

In the Fischer projection, the vertical bonds point away from the observer while the horizontal bonds point towards the observer.

When determining the configuration, the molecule is oriented such that the lowest ranked atom points away from the observer.

The order of decreasing priorities of the three other atoms or groups is decided. If it traces a clockwise path, the configuration is R and if it traces a counterclockwise path, the configuration is S.

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