ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
ORGANIC CHEMISTRY-PACKAGE >CUSTOM<
10th Edition
ISBN: 9781260028355
Author: Carey
Publisher: MCG CUSTOM
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Chapter 4, Problem 37P
Interpretation Introduction

Interpretation:

Stereochemistry of the drug droxidopa is to be shown using appropriate wedges and dashes in such a way that the configurations C2 and C3 are S and R respectively.

Concept introduction:

On the basis of Cahn-Ingold-Prelog (CIP) rules, the absolute configuration at a chiral center is determined.

After orienting the molecule such that the lowest priority group is away from the observer, if atom/group priorities excluding the lowest priority group follow a clockwise path, the absolute configuration is R. If the path followed is counterclockwise, the absolute configuration is S.

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