Interpretation:
The specific rotation of the given compound has to be calculated.
Concept introduction:
The pair of Enantiomers has different configurations.
Pair of enantiomers has different optical activity, which means if one will show levorotatory then the other will show dextrorotatory.
The direction and magnitude of rotation of plane-polarized light by an optically compound is measured by using polarimeter.
This rotation of polarized light is specific for a compound at specified temperature and wavelength, so it is called as Specific rotation of that compound.
Specific rotation of compound is calculated by,
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Organic Chemistry (8th Edition)
- A solution o 150.0 mL of solvent. A portion of the solution was placed in a tube that is 1.00 dm long. chiral compound was prepared by dissolving 25.42 g in What is its specific rotation of light if the observed rotation was determined experimentally to be 15.00°? pinepdf (31).pdf Type here to searcharrow_forwardAn aqueous solution containing 10 g of an optically pure compound was diluted to 500 mL with water and was found to have a specific rotation of −121º. If this solution were mixed with 500 mL of a solution containing 3 g of a racemic mixture of the compound, what would the specific rotation of the resulting mixture of the compound? What would be its optical purity?arrow_forwardQuestion: What is the impact of molecular chirality on the pharmacological activity of drugs, and how can it be harnessed for the development of more effective therapeutic agents?arrow_forward
- At each wavelength, the Beer-Lambert equation states that absorbance is proportional to concentration. For quantitative concentration estimations, any wavelength might theoretically be used. However, we usually choose the wavelength with the highest absorbance for a specific sample and utilize that in our absorbance measurements. The steeper parts of the spectrum should be avoided. Why?arrow_forwardA student isgiven a solution labeled only as 2,3-dihydroxybutane. She used the polarimeter to determine its optical rotation, and found that the solution was not optically active. Draw the absolute configuration of theisomer of 2,3-dihydroxybutane that would give zero optical rotation.arrow_forward11) Label all chiral centers in the following molecule as R or S F Br .....arrow_forward
- app:10Tack.co Type here to se OM C O Quin 23 of 30 A solution of a chiral compound was prepared by dissolving 15.67 g in 16.00 mL of solvent. The solution was placed in a tube that is 1.00 dm long. What is the specific rotation of light if the observed rotation was determined experimentally to be +62.41"? ✓ O 1 4 7 2 5 3 6 9 0 DAộ c * ▪ ✪ с x 100 1508227arrow_forwardQuestion: Explain the concept of chirality in chemistry and its importance in drug development. Additionally, provide an example of a chiral drug and discuss the challenges associated with its synthesis and administration.arrow_forwardApplications of NMR spectroscopy in pharmaceutical analysis Can potentially be used for fingerprinting mixtures Has good potential for non-destructive quantitative analysis of drugs in formulations without prior separation Can determine impurities, including enantiomeric impurities, without separation Powerfull technique for the characterization og the exact structure of raw materials, intermediates, and finished productsarrow_forward
- If we measure the rotation angle of a sample in a polarimeter and it is zero, the sample….(1). It is a 1.00 M aqueous solution of a pure substance of rotational power exactly equal to 100.(2). It is optically inactive.(3). It is an equimolar mixture of enantiomers of the same compound.(4). It is a mixture of right-handed and left-handed substances.arrow_forwardAttach a schematic diagram showing the procedure involved in the determination of observed rotation and calculation of specific rotation.arrow_forwardGive answer and detailed handwritten explanation of the answer!arrow_forward
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