Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 4, Problem 20P

Brachydactyly type D is a human autosomal dominant condition in which the thumbs are abnormally short and broad. In most cases, both thumbs are affected, but occasionally just one thumb is involved. The accompanying pedigree shows a family in which brachydactyly type D is segregating. Filled circles and squares represent females and males who have involvement of both thumbs. Halffilled symbols represent family members with just one thumb affected.

Chapter 4, Problem 20P, Brachydactyly type D is a human autosomal dominant condition in which the thumbs are abnormally

a. Is there any evidence of variable expressivity in this family? Explain.

b. Is there evidence of incomplete penetrance in this family? Explain.

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Genetic Analysis: An Integrated Approach (3rd Edition)

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