Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
bartleby

Concept explainers

Question
Book Icon
Chapter 32, Problem 8P
Interpretation Introduction

Interpretation:

The model of neurotransmitter release needs to be explained.

Concept Introduction :

Number of neurotransmitters are stored in the synaptic vesicles that are unconfined at the synapse. The voltage dependent calcium channel controls this release. The necessary nerve impulses are circulated by the vesicles between the neutrons and recreated in the cell.

Blurred answer
Students have asked these similar questions
Many enzymes can hydrolyze GTP between the β and γ phosphates. The GTP analog β,γ-imidoguanosine 5′-triphosphate (Gpp(NH)p), shown below, cannot be hydrolyzed between the β and γ phosphates. Predict the effect of microinjection of Gpp(NH)p into a myocyte on the cell’s response to β-adrenergic stimulation.
Based on the same attached figure as in question 1 above (Figure 6.8A-B in your textbook) describing the NMDA receptor, a ligand-gated ion channel for glutamate, why does the current versus voltage response described by the red line go from near zero to a negative current at around -50 mV? (A) Channel pore Glutamate Mg2+ (B) EPSC (PA) 150 100 50 0 -50 -100 -150 Hyperpolarized, Mg2+ blocks ORA Glutamate + Mg2+ 0/ + Na Ca²+ Glutamate, no Mg2+ Depolarized, no Mg2+ block while K+ 100 Mg2+
2+ Activation of 5-HT2A Increases cytosolic free Ca²+ Concentration ([Ca²+]) Via a Signaling cascade. At rest, neurons have a cytosolic Ca Concentration of 100nM. The ex- Tra cellular free calcium concentration is typically 1.2m M. Calculate the resting potential (at equilibrium) produced by the neuron as a result of the calcium ion concentration gradient. (Report your answer in mV ).
Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
  • Text book image
    Biochemistry
    Biochemistry
    ISBN:9781305577206
    Author:Reginald H. Garrett, Charles M. Grisham
    Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning