Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 3, Problem 29ESP
Albinism, caused by a mutational disruption in melanin (skin pigment) production, has been observed in many species, including humans. In 1991, and again recently in 2017, the only documented observations of an albino humpback whale (named “Migaloo”) were observed near New South Wales. Recently, Polanowski and coworkers (Polanowski, A., S. Robinson-Laverick, and D. Paton. (2012). Journal of Heredity 103:130–133) studied the genetics of humpback whales from the east coast of Australia, including Migaloo.
- (a) Do you think that Migaloo’s albinism is more likely caused by a dominant or recessive mutation? Explain your reasoning.
- (b) What data would be helpful in determining the answer to part(a)?
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Steven Frank and Laurence Hurst argued that a cytoplasmically inherited mutation in humans that has severe effects in males but no effect in females will not be eliminated from a population by natural selection because only females pass on mtDNA (S. A. Frank and L. D. Hurst. 1996. Nature 383:224). Using this argument, explain why males with Leber hereditary optic neuropathy are more severely affected than females.
Steven Frank and Laurence Hurst argued that a cytoplasmically inherited mutation in humans that has severe effects in males but no effect in females will not be eliminated from a population by natural selection because only females pass on mtDNA. Using this argument, explain why males with Leber hereditary optic neuropathy are more severely affected than females.
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Chapter 3 Solutions
Concepts of Genetics (12th Edition)
Ch. 3 - Pigeons may exhibit a checkered or plain color...Ch. 3 - Considering the Mendelian traits round versus...Ch. 3 - Using the forked-line, or branch diagram, method,...Ch. 3 - In one of Mendels dihybrid crosses, he observed...Ch. 3 - The following pedigree is for myopia...Ch. 3 - If they seek genetic counseling, what issues would...Ch. 3 - If you were in Thomass position, would you want to...Ch. 3 - If Thomas tests positive for the HD allele, should...Ch. 3 - HOW DO WE KNOW? In this chapter, we focused on the...Ch. 3 - CONCEPT QUESTION Review the Chapter Concepts list...
Ch. 3 - Albinism in humans is inherited as a simple...Ch. 3 - Which of Mendels postulates are illustrated by the...Ch. 3 - Discuss how Mendels monohybrid results served as...Ch. 3 - What advantages were provided by Mendels choice of...Ch. 3 - Mendel crossed peas having round seeds and yellow...Ch. 3 - Based on the preceding cross, what is the...Ch. 3 - Which of Mendels postulates can only be...Ch. 3 - In a cross between a black and a white guinea pig,...Ch. 3 - What is the basis for homology among chromosomes?Ch. 3 - In Drosophila, gray body color is dominant to...Ch. 3 - How many different types of gametes can be formed...Ch. 3 - Mendel crossed peas having green seeds with peas...Ch. 3 - In a study of black guinea pigs and white guinea...Ch. 3 - Mendel crossed peas having round green seeds with...Ch. 3 - Prob. 17PDQCh. 3 - The following are F2 results of two of Mendels...Ch. 3 - In assessing data that fell into two phenotypic...Ch. 3 - Prob. 20PDQCh. 3 - Consider the following pedigree. Predict the mode...Ch. 3 - Draw all possible conclusions concerning the mode...Ch. 3 - For decades scientists have been perplexed by...Ch. 3 - A wrongful birth case was recently brought before...Ch. 3 - TaySachs disease (TSD) is an inborn error of...Ch. 3 - Datura stramonium (the Jimsonweed) expresses...Ch. 3 - The wild-type (normal) fruit fly, Drosophila...Ch. 3 - To assess Mendels law of segregation using...Ch. 3 - Albinism, caused by a mutational disruption in...Ch. 3 - (a) Assuming that Migaloos albinism is caused by a...
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY