Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 3, Problem 22PDQ
Draw all possible conclusions concerning the mode of inheritance of the trait portrayed in each of the following limited pedigrees. (Each of the four cases is based on a different trait.)
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Draw all possible conclusions concerning the mode of inheritanceof the trait expressed in each of the following limited pedigrees.(Each case is based on a different trait.)
Consider the two traits: Blood Type B (Parents and Child with Blood Type B, Grandparents unknown) and Earlobe (Father - Hanging; Mother - Attached; Son - Hanging; Grandparents - unkonwn). From these, create a 3-generation pedigree chart include labels for the alleles.What is a possible analysis regarding the mode of inheritance of the observed traits?
What is the most likely pattern of inheritance for this disorder? (Is it autosomal dominant? Autosomal recessive? X-linked dominant? X-linked recessive? Y-linked? Mitochondrial?) Please include two specific pieces of evidence, present within the pedigree, that indicate that this pattern is most likely, as opposed to any other potential pattern. You may assume that the gene responsible for the trait is fully penetrant.
Chapter 3 Solutions
Concepts of Genetics (12th Edition)
Ch. 3 - Pigeons may exhibit a checkered or plain color...Ch. 3 - Considering the Mendelian traits round versus...Ch. 3 - Using the forked-line, or branch diagram, method,...Ch. 3 - In one of Mendels dihybrid crosses, he observed...Ch. 3 - The following pedigree is for myopia...Ch. 3 - If they seek genetic counseling, what issues would...Ch. 3 - If you were in Thomass position, would you want to...Ch. 3 - If Thomas tests positive for the HD allele, should...Ch. 3 - HOW DO WE KNOW? In this chapter, we focused on the...Ch. 3 - CONCEPT QUESTION Review the Chapter Concepts list...
Ch. 3 - Albinism in humans is inherited as a simple...Ch. 3 - Which of Mendels postulates are illustrated by the...Ch. 3 - Discuss how Mendels monohybrid results served as...Ch. 3 - What advantages were provided by Mendels choice of...Ch. 3 - Mendel crossed peas having round seeds and yellow...Ch. 3 - Based on the preceding cross, what is the...Ch. 3 - Which of Mendels postulates can only be...Ch. 3 - In a cross between a black and a white guinea pig,...Ch. 3 - What is the basis for homology among chromosomes?Ch. 3 - In Drosophila, gray body color is dominant to...Ch. 3 - How many different types of gametes can be formed...Ch. 3 - Mendel crossed peas having green seeds with peas...Ch. 3 - In a study of black guinea pigs and white guinea...Ch. 3 - Mendel crossed peas having round green seeds with...Ch. 3 - Prob. 17PDQCh. 3 - The following are F2 results of two of Mendels...Ch. 3 - In assessing data that fell into two phenotypic...Ch. 3 - Prob. 20PDQCh. 3 - Consider the following pedigree. Predict the mode...Ch. 3 - Draw all possible conclusions concerning the mode...Ch. 3 - For decades scientists have been perplexed by...Ch. 3 - A wrongful birth case was recently brought before...Ch. 3 - TaySachs disease (TSD) is an inborn error of...Ch. 3 - Datura stramonium (the Jimsonweed) expresses...Ch. 3 - The wild-type (normal) fruit fly, Drosophila...Ch. 3 - To assess Mendels law of segregation using...Ch. 3 - Albinism, caused by a mutational disruption in...Ch. 3 - (a) Assuming that Migaloos albinism is caused by a...
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- Consider the two traits: Blood Type B (Parents and Child with Blood Type B, Grandparents unknown) and Hanging Earlobe (Parents and Child with Blood Type B, Grandparents unknown). From this, create a 3-generation pedigree chart (starting from grandparents' generation).What is a possible analysis regarding the mode of inheritance of the observed traits?arrow_forwardIn each of the following pedigrees (A, B) by inspection, determine the mode of inheritance involved. Indicate the possible genotypes of all individuals in all the pedigrees.arrow_forwardPlease consider the following pedigree. Assume that people who marry in to the family do not carry the allele unless otherwise indicated. Assume complete penetrance. image attached a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR)(ii) an autosomal dominant allele (AD)(iii) a X-linked recessive allele (XR)(iv) a X-linked dominant allele (XD) b. Provide a set of parents that definitively supports your answers in (a).arrow_forward
- Although in reality the inheritance of cleft chin (e.g., the deep chin dimple seen in Ben Ameck) is slightly more complicated, for now let's assume that the presence or absence of a cleft chin is determined by one gene. By studying pedigrees, we know that no child possesses a cleft chin unless at least one parent does (either the mom or the dad). Hint: Based on that last statement, you should now know the mode of inheritance! What is it? (Remember Recessive traits can hide, but dominant traits never do! ) O Cleft chin is a dominant trait. O Cleft chin is a recessive trait.arrow_forwardAlong with the trait in the pedigree, individual IV-6 and the woman are also both heterozygous for the autosomal dominant allele causing Huntington's disease. If they have a child, what is the probability that it will be affected by at least one of these traits? Remember to include both the trait in the pedigree and Huntington's disease in your calculations. Enter your answer to two decimal places (e.g., 0.55).arrow_forwardLorenzo has a double row of eyelashes (MIM 126300) which he inherited from his mother as a dominant trait. His maternal grandfather is the only other relative to have it. Fatima, who has normal eyelashes, marries Lorenzo. The first child, Nicola (girl) has normal eyelashes. Now Fatima is pregnant again and hopes for a child with double eyelashes. What chance does the child have of inheriting double eyelashes? Draw a pedigree of this family.arrow_forward
- In each of the following pedigrees (C, D) by inspection, determine the mode of inheritance involved. Indicate the possible genotypes of all individuals in all the pedigrees.arrow_forwardThe pedigree below tracks the inheritance of a genetic disorder through a family's generation. Determine the probable inheritance mode for the trait shown in the affected individual (the shaded symbols) by answering the following questions. I II 2 3 4 5 7 III 2 3 6 7 8 5 (i) Based on the pedigree, Y-linked inheritance can be excluded at a glance. Give your reason. (ii) What TWO (2) other modes of inheritance can be definitely excluded? Explain your answer. Of the remaining modes of inheritance, which is the most likely? Which is less likely? Explain your answers. (ii)arrow_forwardA prospective father has two dominant traits dependent on single autosomal genes, cataract (an eye abnormality), which he inherited from his mother, and polydactyly (extra fingers and/or toes), which he inherited from his father. If the loci for these two traits are very closely linked, which of the following possibilities would the man's child be more likely to have (assume his partner is unaffected by either condition): Select one: either cataract or polydactyly both cataract and polydactyly neither traitarrow_forward
- Please consider the following pedigree. Assume that people who marry in to the family do not carry the allele unless otherwise indicated. Assume complete penetrance. I II 5 6 III 6 IV 1 2 a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR) (ii) an autosomal dominant allele (AD) (iii) a X-linked recessive allele (XR) (iv) a X-linked dominant allele (XD) b. Provide a genotype for individual III-6 for the most likely mode of inheritance as determined in (a).arrow_forwardWhat is the pattern of inheritance? Please Provide a specific reason that justifies your selection of this pattern of inheritance as the correct one, and also explain why each of the other two alternatives are not correct. As part of your answer, you must include the phenotypic ratio, including the sex of the offspring, that you would expect to find in each of the three possible scenarios. Please specify whether this pattren of inheritance is (i) rare X-linked recessive, (ii) sex-influenced, or (iii) sex-limited.arrow_forwardPlease consider the following pedigree. Assume that people who marry in to the family do not carry the allele. Assume complete penetrance. I II III 3 IV 1 2 a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR) (ii) an autosomal dominant allele (AD) (iii) a X-linked recessive allele (XR) (iv) a X-linked dominant allele (XD) b. Based strictly on the characteristic patterns of inheritance that define the four different options in (a), give a definitive motivation for the most likely mode of inhertance.arrow_forward
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