ACHIEVE:INTRO TO GENETIC ANALYSIS 1TERM
ACHIEVE:INTRO TO GENETIC ANALYSIS 1TERM
12th Edition
ISBN: 9781319401399
Author: Griffiths
Publisher: MAC HIGHER
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Chapter 3, Problem 19P

A.

Summary Introduction

To determine: The tRNAs encoded by the three different organelles participate in protein synthesis in the cytosol.

Introduction: Transcription is the first of the overall two protein synthesis steps. During transcription, the information encoded in the DNA is copied to an RNA molecule as one strand of the DNA double helix is used as a template.

B.

Summary Introduction

To determine: The organelle has the largest proportion of nongenic DNA.

Introduction: The cell organelles are made up of Ribosomes composed of about equal amounts of rRNA that is ribosomal ribonucleic acid, and proteins, with a little proportion of lipids and specific metallic ions.

C.

Summary Introduction

To determine: The main reason for the difference in size of yeast and human mtDNA.

Introduction: The protein synthesis from amino acid sequences specified by the series of codons in messenger RNA is called translation. The translation is the first stage of protein biosynthesis.

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Suppose that you are studying the role of Protein B, which you believe plays a role in regulating PCD/Apoptosis in mice. You create two lines of mutant mice. One (bb) is homozygous for a loss-of-function allele of gene B. The other (Bb) is heterozygous, with one wild-type allele and one loss-of function allele. Initially you pay particular attention to two phenotypes of the resulting mice:(i) The morphology of their paws (see picture) (ii) The size of their brains & shape of their skulls. The bb mice have unusually large brains and unusual protrusions from their skulls. Based on these data, does it appear that Protein B, when present and active, favors or inhibits PCD/Apoptosis?Briefly explain your reasoning. The answer should address both the paw and brain/skull data.
Suppose that you are studying the role of Protein B, which you believe plays a role in regulating PCD/Apoptosis in mice. You create two lines of mutant mice. One (bb) is homozygous for a loss-of-function allele of gene B. The other (Bb) is heterozygous, with one wild-type allele and one loss-of function allele. Initially you pay particular attention to two phenotypes of the resulting mice:(i) The morphology of their paws (see picture)(ii) The size of their brains & shape of their skulls. The bb mice have unusually large brains and unusual protrusions from their skulls. Suggest one other aspect of mouse morphology or physiology that you might expect to be altered in the absence of Protein B. Briefly explain your reasoning. Also, based on the apparent effect of Protein B on the likelihood of PCD/Apoptosis, would you classify Protein B as the product of a proto-oncogene or of a tumor suppressor gene?
Based on the data in Table 1, which individual(s) is/are heterozygous? Select all that apply   a) B IV-8 b) C IV-3 c) B IV-9 d) A IV-3

Chapter 3 Solutions

ACHIEVE:INTRO TO GENETIC ANALYSIS 1TERM

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