Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Textbook Question
Chapter 3, Problem 11P
Describe the role of the following structures or proteins in cell division:
a. microtubules
b. cohesin protein
c. kinetochores
d. synaptonemal complex
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The following diagram is meant to help you understand how the amount of DNA in a cell changes as the cell cycle progresses. On the diagram, identify two of the stages of the cell
cycle being described and identify how much DNA exists per cell, where a cell is defined as a distinct nucleus. Note that the sequence of images highlights one of the chromosomes
of the cell. The other chromosomes, while also present, are faded in the background.
Stage in Cell Cycle:
A
Status of Chromosomes: (Only one of the chromosomes is intensely colored)
NANA
INNNNNNN
wwwww
wwwNYA
wwwww
WXXXX
VANNNNNN
www
Amount of DNA Per Cell:
C
NNNNA
NNNNNN
WWXXXXX
NNNNNNE
WNNNN
www
B
NNNNN
Between 1X and 2X
2X
D
1X
1) What phase of mitosis is this?
Answer:
2) What is the indicated structure 1? select one.
a. chromosome
b. chromosome with two sister chromatids
c. centrioles/centrosome
d. spindle fibres
e. metaphase plate
3)If the diploid (2n) number of this cell is 8 how many chromosomes are present?
4) If the diploid (2n) number of this cell is 8 how many sister chromatids are present?
5) If the diploid (2n) number of this cell is 8 how many homologous pairs are present?
Name the phases of the cell cycle. b) During which phases are the chromosomes and then the cytoplasm split, respectively? c) Describe one mechanism that is used to regulate the cell cycle.
Chapter 3 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 3 - Examine the following diagrams of cells from an...Ch. 3 - Our closest primate relative, the chimpanzee, has...Ch. 3 -
3. In a test of his chromosome theory of...Ch. 3 - Cohesion between sister chromatids, as well as...Ch. 3 - 5. The diploid number of the hypothetical animal...Ch. 3 - 6. An organism has alleles R1 and R2 on one pair...Ch. 3 - Explain how the behavior of homologous chromosomes...Ch. 3 - 8. Suppose crossover occurs between the homologous...Ch. 3 -
9. Alleles A and a are on one pair of autosomes,...Ch. 3 - Prob. 10P
Ch. 3 - Describe the role of the following structures or...Ch. 3 - A womans father has ornithine transcarbamylase...Ch. 3 - In humans, hemophilia A (OMIM 306700) is an...Ch. 3 -
14. A wild-type male and a wild-type female...Ch. 3 - 15. A woman with severe discoloration of her tooth...Ch. 3 - 16. In a large metropolitan hospital, cells from...Ch. 3 - In cats, tortoiseshell coat color appears in...Ch. 3 - 18. The gene causing Coffin–Lowry syndrome (OMIM...Ch. 3 - 19. Four eye-color mutants in Drosophila—apricot,...Ch. 3 - 20. For each pedigree shown,
a. Identify which...Ch. 3 - 21. Use the blank pedigrees provided to depict...Ch. 3 - 22. Figure 3.22 (page 89) illustrates reciprocal...Ch. 3 - 23. In fruit flies, yellow body (y) is recessive...Ch. 3 - 24. In a species of fish, a black spot on the...Ch. 3 - LeschNyhan syndrome (OMIM 300322) is a rare...Ch. 3 - 26. In humans, SRY is located near a...Ch. 3 - 27. In an 1889 book titled Natural Inheritance...Ch. 3 - 28. In Drosophila, the X-linked echinus eye...Ch. 3 - 29. A wild-type Drosophila male and female are...Ch. 3 - 30. Drosophila has a diploid chromosome number of...Ch. 3 - The cell cycle operates in the same way in all...Ch. 3 - 33. Form a small discussion group and decide on...Ch. 3 - 34. Duchenne muscular dystrophy (DMD; OMIM 310200)...Ch. 3 - Prob. 35P
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- Human cells normally have 46 chromosomes. For each of the following stages, state the number of chromosomes and the number of DNA molecules found in these chromosomes that are present in a human cell. a) Metaphase of mitosis Metaphase I of meiosis c) Telophase of mitosis (after cytokinesis)arrow_forwardList three ways in which mitosis differs from meiosos. Be specificarrow_forwardDraw diagrams for each phase of Mitosis in the correct order. Including Mitosis as part of the cell cycle is beneficial but not required. Identify the most important relevant details about each phase. There are at least 2 details or terms associated with each phase. Please use the proper names for parts such as centromeres, spindle fibres, etc.arrow_forward
- Asymmetric cell division often relies on cytoskeletal elements to generate or maintain the asymmetric distribution of cellular factors. In S. cerevisiae, what factor is localized to the bud by myosin motors? In Drosophila neuroblasts, what factors are localized apically by microtubules?arrow_forwardA cell in G1 of interphase has 8 chromatins. How many chromosomes and how many DNA molecules will be found per cell as this cell progresses through the following stages: a) metaphase b) anaphase c) after cytokinesis in mitosis d) metaphase I e) anaphase I f) metaphase II g) anaphase II h) after cytokinesis of meiosis IIarrow_forwardExplain why we can say that M-phase of the cell-cycle is triggered by a positive feedback loop. a) What would the consequences be if cohesins were working normally but condensins were not? and b) what stage of the cell cycle would this cause problems in? Why is it important for the centrosome to duplicate during G1-G2 (interphase) before M phase? The kinetochores serve as a link between the sister chromatids and the microtubules attached to the mitotic spindle. a) How are microtubules still able to exhibit dynamic instability after they are bound to the sister chromatids and b) why is this important to mitosis? As the name suggests, the Anaphase-promoting-complex (APC), promotes the 4th phase of mitosis by separating the sister chromatids so they can travel to separate poles of the cell, and prevents them from being re-zipped together. Describe how APC does these two things (Hint: one involves M-cyclin and the other involves…arrow_forward
- What are the three types of microtubules involved in the formation of the mitotic spindle? Briefly describe the contribution of each to successful cell division.arrow_forwardThe anticancer drug paclitaxel (Taxol), derived from the Pacific Yew, has many effects on mitosis. One of its most powerful effects is that it prevents disassembly of the mitotic spindle, which prevents spindle fibers from shortening. Which phase of mitosis would this directly affect? Why would this stop cell division overall and lead to cell death?arrow_forwardDetermine whether the following figures portray either Mitosis or Meiosis and identify its specific stage of cell division. (e.g. Mitosis- Prophase)arrow_forward
- The interphase is the part of the eukaryotic cell cycle that is most transcriptionally active. Gene regulation during this phase involves changes in the chromatin. a) What is chromatin? b) How can the chromatin structure change?arrow_forward1) Examine the picture of an onion root tip with cells in various stages of the cell cycle. A student claims that interphase is the longest stage of the cell cycle. Another student claims that mitosis is the longest stage. Using evidence from the photo, determine which student is correct and why. A) Mitosis is the longest stage because anaphase requires more time to separate chromatids. B) Interphase is the longest stage because chromosomes are visible in the majority of the cells. C) Mitosis is the longest stage because the majority of the cells in the photo are replicating their DNA. D) Interphase is the longest stage because the majority of the cells in the photo have uncondensed chromatin and are not dividing. Not Gradedarrow_forwardWhat are the two broadest divisions of the cell cycle? What two processes are involved in the actual duplication of the cell?arrow_forward
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