Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 3, Problem 28P
In Drosophila, the X-linked echinus eye
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Miniature wings (Xm) in Drosophila result from an X-linked allele that is recessive to
the allele for long wings (X*). Give the genotypes of the parents in the following
cross:
Male parent
Female parent
Male offspring
Female offspring
Long
Miniature
750 miniature
761 long
O male: X* / X* and female X™ /x+
O male: X*/Xt and female Xm /xm
O male: X*/ Y and female Xm /xm
O male: Xm/ Y and female Xm /xm
In Drosophila, ebony body colour is produced by a recessive gene a and wild-type (gray) body colour by its dominant allele a+. Vestigial wings are governed by a recessive gene vg, and normal wing size (wild type) by its dominant allele vg+. If wild-type dihybrid flies are crossed and produce 256 progeny, how many of these progeny flies are expected in each phenotypic class?
In Drosophila fruit flies, the genes for warped wings (dwp), rumpled bristles (rmp), and pallid wings (pld) are linked. A trihybrid female for all three allleles is crossed with homozygous recessive male for all three alleles and the offspring obtained showed the following phenotypes:
3 pld rmp dwp
428 pld rmp +
427 + + dwp
48 + rmp +
47 pld + dwp
23 pld + +
2 + + +
22 + rmp dwp
What is the order and map distance between these three alleles?
Chapter 3 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 3 - Examine the following diagrams of cells from an...Ch. 3 - Our closest primate relative, the chimpanzee, has...Ch. 3 -
3. In a test of his chromosome theory of...Ch. 3 - Cohesion between sister chromatids, as well as...Ch. 3 - 5. The diploid number of the hypothetical animal...Ch. 3 - 6. An organism has alleles R1 and R2 on one pair...Ch. 3 - Explain how the behavior of homologous chromosomes...Ch. 3 - 8. Suppose crossover occurs between the homologous...Ch. 3 -
9. Alleles A and a are on one pair of autosomes,...Ch. 3 - Prob. 10P
Ch. 3 - Describe the role of the following structures or...Ch. 3 - A womans father has ornithine transcarbamylase...Ch. 3 - In humans, hemophilia A (OMIM 306700) is an...Ch. 3 -
14. A wild-type male and a wild-type female...Ch. 3 - 15. A woman with severe discoloration of her tooth...Ch. 3 - 16. In a large metropolitan hospital, cells from...Ch. 3 - In cats, tortoiseshell coat color appears in...Ch. 3 - 18. The gene causing Coffin–Lowry syndrome (OMIM...Ch. 3 - 19. Four eye-color mutants in Drosophila—apricot,...Ch. 3 - 20. For each pedigree shown,
a. Identify which...Ch. 3 - 21. Use the blank pedigrees provided to depict...Ch. 3 - 22. Figure 3.22 (page 89) illustrates reciprocal...Ch. 3 - 23. In fruit flies, yellow body (y) is recessive...Ch. 3 - 24. In a species of fish, a black spot on the...Ch. 3 - LeschNyhan syndrome (OMIM 300322) is a rare...Ch. 3 - 26. In humans, SRY is located near a...Ch. 3 - 27. In an 1889 book titled Natural Inheritance...Ch. 3 - 28. In Drosophila, the X-linked echinus eye...Ch. 3 - 29. A wild-type Drosophila male and female are...Ch. 3 - 30. Drosophila has a diploid chromosome number of...Ch. 3 - The cell cycle operates in the same way in all...Ch. 3 - 33. Form a small discussion group and decide on...Ch. 3 - 34. Duchenne muscular dystrophy (DMD; OMIM 310200)...Ch. 3 - Prob. 35P
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- In Drosophila, the sepia mutation (se, chromosome 3, position 26) results in dark brown eyes, while cinnabar (cn, chromosome 2, position 57.5) results in bright orange-red eyes. True breeding, wild type females are mated with true breeding males homozygous recessive for both traits. Using Drosophila notation, diagram the P1 and F1 crosses. P1 F1 Fill in the chart with phenotypic ratios that would be expected in the F2 generation. Use the space provided to show your work. Phenotype Females Males Overall (♀and ♂) =1 =1arrow_forwardIn Drosophila, singed bristles (sn) and cut wings (ct) are both caused by recessive, X-linked alleles. The wild type alleles (sn+ and ct+) are responsible for straight bristles and intact wings, respectively. A female homozygous for sn and ct+ is crossed to a sn+ct male. The F1 flies are interbred. The F2 males are distributed as follows: genotype number sn ct 15 sn ct+ 34 sn+ ct 33 sn+ct+ 18 What is the map distance between sn and ct?arrow_forwardMiniature wings (Xm) in Drosophila result from an X-linked allele that is recessive to the allele for long wings (X*). Give the genotypes of the parents in the following cross: Male parent Female parent Male offspring Female offspring 231 long, 250 miniature Long Long 560 long O male: Xm/Y and female X* /X* male: X* / Y and female Xm /x O male: X* /Y and female X* /X* male: Xm/Y and female Xm /x+arrow_forward
- In Drosophila, singed bristles (sn) and cut wings (ct) are both caused by recessive, X-linked alleles. The wild type alleles (sn+ and ct+) are responsible for straight bristles and intact wings, respectively. A female homozygous for sn+ and ct+ is crossed to a sn ct male. The F1 flies are interbred. The F2 males are distributed as follows sn ct 36 sn ct+ 13 sn+ ct 12 sn+ ct+ 39 What is the map distance between sn and ct?arrow_forwardA mutant sex-linked trait called “notched” (N) is deadly in Drosophila when homozygous in females. Males who have a single N allele will also die. The heterozygous condition (Nn) causes small notches on the wing. The normal condition in both male and females is represented by the allele n. a) Indicate the phenotypes of the F1 generation from the following cross: XNXn x XnY b) Explain why dead females are never found in the F1 generation no matter which parents are crossed. c) Explain why the mating of female XNXn and a male XNy is unlikely.arrow_forwardIn Drosophila, an X-linked recessive mutation, Xm causes miniature wings. List the F2 phenotypic ratios if: a miniature-winged female is crossed with a normal male and a miniature-winged male is crossed with a normal female. What would the phenotypic ratio from (a) be if the miniature-winged gene were autosomal? Assume in all cases that the P1 individuals are true-breeding.arrow_forward
- The phenotype of vestigial (short) wings (vg) in Drosophila melanogaster is caused by a recessive mutant gene that independently assorts with a recessive gene for hairy (h) body. Assume that a cross is made between a fly that is homozygous for normal wings and has a hairy body and a fly with vestigial wings that is homozygous for normal body. The wild-type F1 flies were crossed among each other to produce 1024 F2 offspring. Which phenotypes would you expect among the F2 offspring, and how many of each phenotype would you expect? Group of answer choices 192 wild type, 256 vestigial, 64 hairy, and 192 vestigial and hairy All vestigial and hairy. 576 wild type, 192 vestigial, 192 hairy, and 64 vestigial and hairy All wild type 256 wild type; 256 vestigial, 256 hairy, and 256 vestigial and hairyarrow_forwardIN DROSOPHILA, AN X-LINKED RECESSIVE MUTATION, Xm CAUSES MINIATURE WINGS. LIST THE F₂ PHENOTYPIC RATIOS IF: A MINIATURE-WINGED FEMALE IS CROSSED WITH A NORMAL MALE AND A MINIATURE-WINGED MALE IS ● ● CROSSED WITH A NORMAL FEMALE. WHAT WOULD THE PHENOTYPIC RATIO FROM (A) BE IF THE MINIATURE- WINGED GENE WERE AUTOSOMAL? ASSUME IN ALL CASES THAT THE P1 INDIVIDUALS ARE TRUE-BREEDING.arrow_forwardIn Drosophila, the white gene located on the X chromosome affects eye color; an autosomal gene, wingless, is on an autosomal chromosome. Use the following allele symbols: Xw+ _ , Xw+Y = wild type red eyes; X-linked dominant allele Xw Xw , XwY = white eyes; X-linked recessive allele Y = Y sex chromosome vg+ = wild type wings; autosomal dominant vg = wingless; autosomal recessive Predict ratios/proportions of genotypes and phenotypes of offspring from the following cross, of a white-eyed male with wild type wings and a wild type red eyed female with wild type wings: indicate sex of offspring along with phenotypes. XwY vg+ vg x Xw+Xw vg+vgarrow_forward
- Table (see attached image) Diagram the cross showing the segregation of genes responsible for eye-color in Drosophila. Indicate all applicable ene relationships. Indicate the genotypes, phenotypes and gametes of individuals involved in all crosses. Indicate the genotypic and phenotypic ratios of the F2 generation.arrow_forwardIn Drosophila, the fruit fly, white eyes are determined by a recessive X-linked gene and the wild-type or normal brick-red eyes are due to its dominant allele. Use symbols of the following types: XrY = a white-eyed male; XRXR = a homozygous normal red female Show the genotypes and list the phenotypes of the F1 offspring Now, cross the F1 offspring. Show the genotypes and list the phenotypes of the F2 offspring.arrow_forwardThree recessive mutations in Drosophila melanogaster, roughoid (ru, small rough eyes), javelin (jv, cylindrical bristles), and sepia eyes (se, dark brown eyes) are linked. A three-point cross was carried out and the following progeny obtained: jv+ ru+ se+ 37 jv+ ru+ se 2 jv+ ru se 14 jv+ ru se+ 146 jv ru se+ 2 jv ru se 35 jv ru+ se 154 jv ru+ se+ 10 a. Determine the order of the genes on the chromosome. b. Determine which progeny contain single crossovers and which contain double crossovers and indicate where among the genes the crossovers occurred. c. Calculate the map distances among the genes. d. Calculate the coefficient of coincidence and interference among the genesarrow_forward
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