Chapter 27.4, Problem 5P

Interpretation Introduction

Interpretation:

To assign R or S configuration to each chirality center in prostaglandin E2, the most abundant and biologically potent of mammalian prostaglandins.

Concept introduction:

The prostaglandins are a group of C₂₀ lipids that contain a five-membered ring with two long side chains. They have wide range of biological functions like lowering blood pressure, affect blood platelet aggregation during clotting, lower gastric secretions, control inflammation, affect kidney function, affect reproductive systems, and stimulate uterine contractions during childbirth.

To determine:

To assign R or S configuration to each chirality center in prostaglandin E2.