Concept explainers
To discuss:
Mitochondrial proton pumps, the chemiosmotic mechanism, and ATP synthase in producing ATP.
Introduction:
Mitochondria have two membranes: one is the outer mitochondrial membrane and the other is the inner mitochondrial membrane. Between these two membranes, there is a mitochondrial membrane space. Mitochondrial matrix is present inside the mitochondria. NADH and FADH2 are synthesized in the cytoplasm and the mitochondrial matrix, through glycolysis and Krebs cycle. These high energy compounds enter the inner mitochondrial membrane, transport the electrons in the electron transport chain, produce H2O from oxygen, and produce ATP molecules. An electron transport molecule has four enzyme complexes that are used for the transfer of enzyme molecules for the production of ATP and water molecules.
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Anatomy & Physiology: The Unity of Form and Function
- mechanistic interaction between electron transport chain and oxidative phosphorylation to produce ATP in skeletal musclearrow_forwardThe F-class ATP synthase and the V-class proton pumps are similar in many ways. How are they different? their subunit composition the ion with which they interact none of the above their subcellular localizationarrow_forwardactive transport when no ATP is available is faster than when ATP is available true or false?arrow_forward
- Cellular location where TCA Cycle reactions occur. Cytoplasm O Endoplasmic Reticulum Mitochondrial Matrix O Nucleusarrow_forwardThe enzyme responsible for the 1st committed step in the glycolytic pathwayarrow_forwardThe chemical coupling hypothesis (substrate-level phosphorylation) failed to explain why mitochondrial membrane mustbe intact during ATP synthesis. How does the chemiosmotictheory account for this phenomenon?arrow_forward
- Explain the chemiostic mechanism of ATP generation.arrow_forwardWhy each (oxidation) FADH2 in the respiratory chain makes fewer ATP in comparison to oxidation of NADH molecule. 1. Talk about the electron transport complexes. 2. How many protons are pumped for each complex?arrow_forwardComplexes I and II of the electron transport system transferelectrons from NADH and succinate from _______________,respectively, to UQ.arrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning