CONNECT IA GENERAL ORGANIC&BIO CHEMISTRY
4th Edition
ISBN: 9781260562620
Author: SMITH
Publisher: MCG
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Chapter 23, Problem 47P
The conversion of isocitrate to
![Chapter 23, Problem 47P, The conversion of isocitrate to ketoglutarate in step [3] of the citric acid cycle actually occurs](http://dev-ingestion-image-output.s3-website-us-east-1.amazonaws.com/9781259883989/Chapter-23/images/html_83989-23-47p_image001.jpg)
a. Classify reaction [3a] as an oxidation, reduction, or decarboxylation.
b. Classify reaction [3b] as an oxidation, reaction, or decarboxylation.
c. For which step is
d. Why is the enzyme that catalyzes this reaction called isocitrate dehydrogenase?
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Students have asked these similar questions
Refer to the structure
1. The metabolic pathway is an example of
a. Oxidative dealkylation
b. Reduction
c. Oxidative deamination
d. Hydrolysis
2. This pathway is true for what kind of drugs
a. Endogenous amides
b. Endogenous amines
c. Radical species
d. Endogenous amino acids
Draw structures of three possible Phase I metabolites of the following molecule. Name the
reactions involved in each of the three metabolic pathways that you proposed.
N.
N-CH3
GLYCOLYSIS:
1A) Starting with glucose (in the open-chain Fisher projection), draw out the molecular structures for
each step of glycolysis. For each step, include the name of the enzyme that catalyzes the reaction.
1B) What is the net reaction of glycolysis?
CITRIC ACID CYCLE:
2A) Starting with acetyl-coenzymeA and oxaloacetate, draw out the molecular structures for each step
of the citric acid cycle. For each step, include the name of the enzyme that catalyzes the reaction.
2B) What is the net reaction of the citric acid cycle? What happens to each product?
OXIDATIVE PHOSPHORYLATION:
3A) Thoroughly explain the biological significance of NADH/H* and FADH2 and their roles in
oxidative phosphorylation.
3B) Describe and diagram the general pathway of the electrons from NADH/H+ and FADH₂ to O₂
during the electron transport chain.
3C) What is "chemiosmotic coupling", and what is its relationship to ATP synthesis?
3D) During oxidative phosphorylation, what is oxidized and what is…
Chapter 23 Solutions
CONNECT IA GENERAL ORGANIC&BIO CHEMISTRY
Ch. 23.2 - Prob. 23.1PCh. 23.3 - Prob. 23.2PCh. 23.3 - The phosphorylation of glucose to glucose...Ch. 23.3 - Prob. 23.3PCh. 23.3 - Use the values for the hydrolysis of creatine...Ch. 23.4 - Prob. 23.2PPCh. 23.4 - Prob. 23.5PCh. 23.4 - Prob. 23.6PCh. 23.4 - Prob. 23.7PCh. 23.4 - Prob. 23.8P
Ch. 23.5 - Prob. 23.3PPCh. 23.5 - Prob. 23.9PCh. 23.5 - Prob. 23.10PCh. 23.5 - Prob. 23.11PCh. 23.6 - Prob. 23.12PCh. 23.6 - At several points in the electron transport chain,...Ch. 23.6 - In which region of the mitochondrion-the matrix or...Ch. 23 - Prob. 15PCh. 23 - Explain why mitochondria are called the...Ch. 23 - Prob. 17PCh. 23 - Prob. 18PCh. 23 - Prob. 19PCh. 23 - Prob. 20PCh. 23 - What are coupled reactions and why does coupling...Ch. 23 - Prob. 22PCh. 23 - Prob. 23PCh. 23 - Prob. 24PCh. 23 - Prob. 25PCh. 23 - Prob. 26PCh. 23 - Prob. 27PCh. 23 - Prob. 28PCh. 23 - Prob. 29PCh. 23 - Prob. 30PCh. 23 - Prob. 31PCh. 23 - Prob. 32PCh. 23 - (a) Draw the structure of the high-energy...Ch. 23 - Prob. 34PCh. 23 - Classify each substance as an oxidizing agent, a...Ch. 23 - Classify each substance as an oxidizing agent, a...Ch. 23 - When a substrate is oxidized, is NAD+ oxidized or...Ch. 23 - When a substrate is reduced, is FADH2 oxidized or...Ch. 23 - Prob. 39PCh. 23 - Prob. 40PCh. 23 - Prob. 41PCh. 23 - Prob. 42PCh. 23 - Prob. 43PCh. 23 - Prob. 44PCh. 23 - Prob. 45PCh. 23 - Prob. 46PCh. 23 - The conversion of isocitrate to ketoglutarate in...Ch. 23 - Prob. 48PCh. 23 - Prob. 49PCh. 23 - Prob. 50PCh. 23 - Prob. 51PCh. 23 - What is the role of each of the following in the...Ch. 23 - What is the role of each of the following in the...Ch. 23 - Prob. 54PCh. 23 - Prob. 55PCh. 23 - Prob. 56PCh. 23 - Prob. 57PCh. 23 - Prob. 58PCh. 23 - Prob. 59PCh. 23 - Prob. 60PCh. 23 - Prob. 61PCh. 23 - Prob. 62PCh. 23 - Prob. 63PCh. 23 - Prob. 64PCh. 23 - Prob. 65PCh. 23 - Prob. 66PCh. 23 - Prob. 67PCh. 23 - Prob. 68PCh. 23 - Prob. 69PCh. 23 - Prob. 70PCh. 23 - Prob. 71PCh. 23 - Prob. 72PCh. 23 - Prob. 73PCh. 23 - Prob. 74PCh. 23 - Prob. 75CPCh. 23 - Prob. 76CP
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