Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Textbook Question
Chapter 22.1, Problem 2SB
What is clinical variation?
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Frequency of
allele A1
Question 2
The graph below shows results of two simulations, both depicting the rise in
frequency of beneficial allele in a population of infinite size. The selection
coefficient and the starting frequency are the same, but in one simulation the
beneficial allele is dominant and in the other it is recessive. Neither allele is
fixed by 500 generations.
1.0
1
0.8
0.6
0.4
2
0.2
0
0
100
200 300
400
500
Generation
(a) Which simulation shows results for a dominant and which shows results for a
recessive allele? How can you tell? (4 pts)
(b) Neither of the alleles reaches fixation by 500 generations. If given enough
time, will both of these alleles reach fixation in the population? Why or why
not? (3 pts)
12pt
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BIU AT2v
V
Question 14
The relative fitnesses of three genotypes are WA/A= 1.0, WA/a = 0.7, and Wa/a =
0.3. If the population starts at the allele frequency p = 0.5, what is the value of p
in the next generation? (3 pts)
12pt v
V
Paragraph B I U
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V
V
p
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According to a recent study, 1 out of 50,000 people will be diagnosed with
cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene
(dominant gene symbol is F and mutant is f).
A. Using the rate of incidence above, what is the frequency of carriers of the
cystic fibrosis allele for CFTR in the US? (3 pts)
B. In a clinical study, 400 people from the population mentioned in (A.) were
genotyped for BRCA1 Listed below are the results. Are these results in Hardy-
Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts)
BRCA1 genotype
# of women
390
BB
Bb
bb
10
0
12pt
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Chapter 22 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 22.1 - How do the morphological, biological, and...Ch. 22.1 - What is clinical variation?Ch. 22.2 - What is the difference between prezygotic and...Ch. 22.2 - Prob. 2SBCh. 22.3 - Prob. 1SBCh. 22.3 - Why might insects from different host races be...Ch. 22.4 - Prob. 1SBCh. 22.4 - Prob. 2SBCh. 22 - The biological species concept defines species on...Ch. 22 - Prob. 2TYK
Ch. 22 - A characteristic that exhibits smooth changes in...Ch. 22 - Prezygotic is isolating mechanisms: a. reduce the...Ch. 22 - In the model of allopatric speciation, the...Ch. 22 - Prob. 6TYKCh. 22 - If two species of holly (genus Ilex) flower during...Ch. 22 - Prob. 8TYKCh. 22 - An animal breeder, attempting to cross a llama...Ch. 22 - Prob. 10TYKCh. 22 - Apply Evolutionary Thinking How do human...Ch. 22 - Prob. 12TYKCh. 22 - Prob. 13TYKCh. 22 - Prob. 14TYKCh. 22 - Prob. 15TYKCh. 22 - David Hills of Baylor University noted that three...
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