SEELEY'S ANATOMY+PHYSIOLOGY
12th Edition
ISBN: 9781260172195
Author: VanPutte
Publisher: RENT MCG
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Chapter 22, Problem 3CT
If the thymus of an adult experimental animal is removed. the followingobservations can be made: (a) No immediate effect occurs, and (b) after 1 year, decreases occur in the number of lymphocytes in the blood, theability to reject grafts, and the ability to produce antibodies. Explain these observations.
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If the thymus of an adult experimental animal is removed, the following observations can be made: (a) No immediate effect occurs, and (b) after 1 year, decreases occur in the number of lymphocytes in the blood, the ability to reject grafts, and the ability to produce antibodies. Explain these observations.
A white cell differential was performed for an adult female, with the following percentages of cells counted:Neutrophils = 25%, Lymphocytes = 69%, Monocytes = 5%, Eosinophils = 1%, Basophils = <1%Given that the total white cell count for this individual is 8.1x109/L, calculate the absolute number of lymphocytes per litre of blood. Discuss possible causes for any of the white cell differential counts which do not fall within the expected reference ranges.
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Chapter 22 Solutions
SEELEY'S ANATOMY+PHYSIOLOGY
Ch. 22.1 - Prob. 1AYPCh. 22.2 - Name the parts of the lymphatic system.Ch. 22.2 - How is lympn formed?Ch. 22.2 - Describe the structure of a lymphatic capillary....Ch. 22.2 - What is the function of valves in lymphatic...Ch. 22.2 - Prob. 6AYPCh. 22.2 - Prob. 7AYPCh. 22.2 - Prob. 8AYPCh. 22.2 - Prob. 9AYPCh. 22.2 - Prob. 10AYP
Ch. 22.2 - Describe the structure, function, and location of...Ch. 22.2 - Where are lymph nodes found? Describe the parts of...Ch. 22.2 - Prob. 13AYPCh. 22.2 - Prob. 14AYPCh. 22.2 - Prob. 15AYPCh. 22.2 - Prob. 16AYPCh. 22.3 - Prob. 17AYPCh. 22.3 - Why do specificity and memory relate to adaptive...Ch. 22.3 - What are the differences between innate immunity...Ch. 22.4 - List the three components of innate immunity.Ch. 22.4 - Prob. 21AYPCh. 22.4 - Prob. 22AYPCh. 22.4 - Prob. 23AYPCh. 22.4 - Prob. 24AYPCh. 22.4 - Prob. 25AYPCh. 22.4 - Prob. 26AYPCh. 22.4 - What effects are produced by the chemicals...Ch. 22.4 - Prob. 28AYPCh. 22.4 - Prob. 29AYPCh. 22.4 - Describe the events that take place during an...Ch. 22.4 - Prob. 31AYPCh. 22.5 - Prob. 32AYPCh. 22.5 - Prob. 33AYPCh. 22.5 - What are the two types of adaptive immunity?Ch. 22.5 - Prob. 35AYPCh. 22.5 - Prob. 36AYPCh. 22.5 - What are the primary lymphatic organs? What are...Ch. 22.5 - Prob. 38AYPCh. 22.5 - Prob. 39AYPCh. 22.5 - Prob. 40AYPCh. 22.5 - Prob. 41AYPCh. 22.5 - Prob. 42AYPCh. 22.5 - Prob. 43AYPCh. 22.5 - Prob. 44AYPCh. 22.5 - Prob. 45AYPCh. 22.5 - Prob. 46AYPCh. 22.5 - Prob. 47AYPCh. 22.5 - What are the functions of the variable and...Ch. 22.5 - Prob. 49AYPCh. 22.5 - Prob. 50AYPCh. 22.5 - Prob. 51AYPCh. 22.5 - Prob. 52AYPCh. 22.5 - Prob. 53AYPCh. 22.5 - Prob. 54AYPCh. 22.5 - Prob. 55AYPCh. 22.5 - Prob. 56AYPCh. 22.6 - Prob. 57AYPCh. 22.6 - Prob. 58AYPCh. 22.6 - Prob. 59AYPCh. 22.6 - Prob. 60AYPCh. 22.7 - Prob. 61AYPCh. 22.8 - Prob. 62AYPCh. 22.9 - What effect does aging have on the major functions...Ch. 22.9 - Prob. 64AYPCh. 22 - The lymphatic system a. removes excess fluid from...Ch. 22 - Which of the following statements is correct? a....Ch. 22 - Prob. 3RACCh. 22 - Prob. 4RACCh. 22 - Prob. 5RACCh. 22 - Prob. 6RACCh. 22 - Prob. 7RACCh. 22 - Prob. 8RACCh. 22 - Macrophages a. are large, phagocytic cells that...Ch. 22 - Which of these cells in the most important in the...Ch. 22 - Prob. 11RACCh. 22 - Antigens a. are foreign substances introduced into...Ch. 22 - Prob. 13RACCh. 22 - Prob. 14RACCh. 22 - Prob. 15RACCh. 22 - Which of these participates in costimulation? a....Ch. 22 - Prob. 17RACCh. 22 - Prob. 18RACCh. 22 - Prob. 19RACCh. 22 - Prob. 20RACCh. 22 - Prob. 21RACCh. 22 - Prob. 22RACCh. 22 - Prob. 23RACCh. 22 - Prob. 24RACCh. 22 - Prob. 25RACCh. 22 - A patient is suffering from edema in the...Ch. 22 - Prob. 2CTCh. 22 - If the thymus of an adult experimental animal is...Ch. 22 - Prob. 4CTCh. 22 - Prob. 5CTCh. 22 - Prob. 6CTCh. 22 - Prob. 7CTCh. 22 - Prob. 8CTCh. 22 - Prob. 9CTCh. 22 - Upon first exposure to an antigen, a sequence of...
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- For each of the following situations, indicate which type(s) of lymphocyte(s), if any, would be expected to proliferate rapidly in lymph nodes and where in the nodes they would do so. Nomal mouse with a viral infection (a) (b) (c) Neonatally thymectomized mouse immunized with a protein antigen Neonatally thymectomized mouse immunized with the thymus-independent antigen bacterial lipopolysaccharide (LPS), which does not require the aid of THcells to activate B cells.arrow_forwardIf the thymus of an experimental animal is removed immediatelyafter its birth, the animal exhibits the following characteristics:(a) an increased susceptibility to infections, (b) decreased numbers oflymphocytes in lymphatic tissue, and (c) a greatly decreased ability toreject grafts. Explain these observations.arrow_forwardDiscuss in detail the role of CTLA-4 and PD-1/PD-L1; compare and contrast the two pathways in immunotherapy. Do the two pathways play a complementary and/or synergistic roles? Give an example of 1 approved drug for each pathway along with information on immunogenicity, route of administration, dosing regimen, and key PK parameters such as half-life and clearance.arrow_forward
- Briefly explain the significance of RH factor. Why mother with Rh negative blood should receive RhoGAM shot? What type of antibodies would be produced in this case? Why there is no universal donor anymore? What type of blood you can transfuse if patient has type A- blood?arrow_forwardIn a patient of 60 years old after the surgical removal of stomach cancer and subsequent treatment, an enlarged lymph node in the left supraclavicular area was detected. Atypical cells, which were similar to the cells of a previously removed tumor, were found after the biopsy of this lymph node, Questions: 6) Is kind of tumors (benign or malignant) is characterized by the presence of cellular atypism? 7) What are the characteristics of malignant tumors?arrow_forward122. A 2-year-old boy has had recurrent episodes of otitis media and bacterial pneumonia. Serum immunoglobulin concentrations are: 1 mg/dL (N=23-190) 10 mg/dL (N=500-1300) 5 mg/dL (N=50-199) Further testing shows normal phagocytic function and delayed-type hypersensitivity responses. A lymph node biopsy specimen is most likely to show absence of which of the following cells? A) Capillary endothelial cells– IgA IgG IgM B) CD4+ T lymphocytes QC) CD8+ T lymphocytes OD) Dendritic cells E) Plasma cellsarrow_forward
- Nursing care of a patient with acquired immune deficiency syndrome (AIDS) includes monitoring of T-lymphocyte counts. Explain why.arrow_forwardList 2 siutations which will trigger clonal anergy. Why could clonal anergy potentially be beneficial (useful)?arrow_forwardTrue or false: 1. Highly proliferative centroblasts are located in the light-zone rather than the dark zone of the germinal center 2. All memory cells (central memory, effector memory, tissue-resident) have equivalent tissue-homing capacity 3. Effector T cells home to sites of infection through action of tissue-specific chemokines. 4. The differentiation fate of CD4 T cells is pre-determined before activation.arrow_forward
- What is the major problem if self reacting lymphocytes are not eliminated from our body before birth ? Note : ( Problem =Clonal deletion) At least 1 page answer . Explaining how it is a problem. Thank you !arrow_forwardFor each blood type in the table below, fill in the expected agglutination result from mixing the blood with eachof the antibodies.arrow_forwardAn 18-month old has been hospitalized several times because of severe recurrent infections with Candida chronic hypocalcemia, and failure to thrive . Flow cytomegalovirus shows a decreased number of peripheral blood lymphocytes reacting with fluoresceinated anti human IgGand decreased number of CD3+ T lymphocytes. Which of the following is the most likely diagnosis. (A) AIDS. (B). Bruton X-linked agammaglobulinemia. (C) Chronic granulomatous disease. (D) Common Variable Hypogammaglobunemia.…arrow_forward
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