Chapter 22, Problem 22.35P

Interpretation Introduction

(a)

Interpretation: The reagents required to convert phenylacetonitrile $\left({\text{C}}_{\text{6}}{\text{H}}_{\text{5}}{\text{CH}}_{\text{2}}\text{CN}\right)$ to ${\text{C}}_{\text{6}}{\text{H}}_{\text{5}}{\text{CH}}_{\text{2}}{\text{COCH}}_3$ are to be stated.

Concept introduction: Grignard reagents are organometallic compounds having the general formula $\text{RMgX}$ where R can be an alkyl or aryl group and X is a halogen atom.

Interpretation Introduction

(b)

Interpretation: The reagents required to convert phenylacetonitrile $\left({\text{C}}_{\text{6}}{\text{H}}_{\text{5}}{\text{CH}}_{\text{2}}\text{CN}\right)$ to ${\text{C}}_{\text{6}}{\text{H}}_{\text{5}}{\text{CH}}_{\text{2}}\text{COC}{\left({\text{CH}}_3\right)}_3$ are to be stated.

Concept introduction: Grignard reagents are organometallic compounds having the general formula $\text{RMgX}$ where R can be an alkyl or aryl group and X is a halogen atom.

Interpretation Introduction

(c)

Interpretation: The reagents required to convert phenylacetonitrile $\left({\text{C}}_{\text{6}}{\text{H}}_{\text{5}}{\text{CH}}_{\text{2}}\text{CN}\right)$ to ${\text{C}}_{\text{6}}{\text{H}}_{\text{5}}{\text{CH}}_{\text{2}}\text{CHO}$ are to be stated.

Concept introduction: Nitrile groups get converted to carbonyl group in presence of reducing agents like DIBAL-H.

Interpretation Introduction

(d)

Interpretation: The reagents required to convert phenylacetonitrile $\left({\text{C}}_{\text{6}}{\text{H}}_{\text{5}}{\text{CH}}_{\text{2}}\text{CN}\right)$ to ${\text{C}}_{\text{6}}{\text{H}}_{\text{5}}{\text{CH}}_{\text{2}}\text{COOH}$ are to be stated.

Concept introduction: Hydrolysis of nitriles in acidic medium convert them to the corresponding carboxylic acids.