Chapter 21, Problem 17A

Interpretation Introduction

Interpretation:

The denaturation of a protein must be explained. Three examples of situation must be given when proteins are denatured.

Concept Introduction:

Denaturation of protein is the phenomenon in which the protein is coagulated.

Answer to Problem 17A

Denaturation of protein means the process in which secondary, tertiary and quaternary structures are destroyed keeping only the primary structure.

Three examples of situation in which proteins are denatured are heating, pH change and use of chemical.

Explanation of Solution

After the denaturation of proteins the functions of the proteins are lost as secondary, tertiary and quaternary structures are broken. Only the sequence of amino acids is present which are connected by peptide bonds.

Denaturation of protein can takes place at higher temperature. Optimum condition for working of protein is 40°C.

At very high or low pH proteins get denatured. Thus protein can best work at physiological pH which is 7.4.

A chemical can denature protein for example alcohol.