Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 2, Problem 5RQ
Summary Introduction

To review:

Definition of the following terms:

(a) Signal transduction

(b) Neurotransmitter

(c) Hormone

(d) Cytokine

(e) LPS

Introduction:

Cells communicate with each other, which is achieved by signal transduction. Chemical agents that are secreted by neurons are neurotransmitters. Organic substances produced in plants and animals that act to regulate physiological activities are hormones. Cytokines are broad category of small proteins involved in cell signaling. LPS stands for lipopolysaccharides.

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Two tetrapeptides were isolated from a possum's sweat glands. These peptides were sequenced using Edman degradation and the following 2 sequences were obtained: Gly-Asp-Ala-Leu  Gly-Asp-Asp-Leu  Can you please help show the titration curve for both of these peptides and calculate the PI?
Two tetrapeptides were isolated from a possum's sweat glands. These peptides were sequenced using Edman degradation and the following 2 sequences were obtained: Gly-Asp-Ala-Leu  Gly-Asp-Asp-Leu  What is the structure of the PTH derivative produced during the last round of amino acid sequencing?
What is the primary sequence of this undecapeptide? Also,   if x-ray crystallography shows a highly stable hairpin turn within the polypeptide, what about the primary sequence explains this structural feature?
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