GENERAL,ORGANIC, & BIOLOGICAL CHEM-ACCES
4th Edition
ISBN: 9781265982959
Author: SMITH
Publisher: MCG
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Textbook Question
Chapter 19.6, Problem 19.11P
Identify the components of each lipid and classify it as a triacylglycerol, a phosphoacylglycerol, or a sphingomyelin. Classify any phosphoacylglvcerol as acephalin or lecithin.
a.
b.
c.
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Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
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Chapter 19 Solutions
GENERAL,ORGANIC, & BIOLOGICAL CHEM-ACCES
Ch. 19.1 - Prob. 19.1PPCh. 19.1 - Prob. 19.1PCh. 19.2 - (a) Draw a skeletal structure for each fatty acid....Ch. 19.2 - Prob. 19.2PCh. 19.2 - Prob. 19.3PCh. 19.3 - Prob. 19.3PPCh. 19.3 - One component of jojoba oil is a wax formed from...Ch. 19.3 - Explain why beeswax is insoluble in water,...Ch. 19.3 - Prob. 19.6PCh. 19.4 - Prob. 19.4PP
Ch. 19.4 - Prob. 19.7PCh. 19.4 - Prob. 19.8PCh. 19.5 - Prob. 19.5PPCh. 19.5 - Review Section 5.2 on balancing chemical...Ch. 19.5 - Prob. 19.10PCh. 19.6 - Prob. 19.6PPCh. 19.6 - Identify the components of each lipid and classify...Ch. 19.7 - Prob. 19.12PCh. 19.7 - Prob. 19.13PCh. 19.7 - Prob. 19.14PCh. 19.8 - (a) Label the rings of the steroid nucleus in...Ch. 19.8 - Prob. 19.16PCh. 19.8 - Prob. 19.17PCh. 19.9 - Prob. 19.18PCh. 19.9 - Prob. 19.19PCh. 19.10 - Prob. 19.20PCh. 19.11 - Prob. 19.21PCh. 19.11 - Prob. 19.22PCh. 19 - Prob. 23PCh. 19 - Prob. 24PCh. 19 - Prob. 25PCh. 19 - Prob. 26PCh. 19 - Prob. 27PCh. 19 - Prob. 28PCh. 19 - Rank the fatty acids in order of increasing...Ch. 19 - Prob. 30PCh. 19 - Prob. 31PCh. 19 - Prob. 32PCh. 19 - Prob. 33PCh. 19 - Prob. 34PCh. 19 - Draw the structure of a wax formed from palmitic...Ch. 19 - Draw the structure of a wax formed from a...Ch. 19 - What hydrolysis products are formed when each wax...Ch. 19 - What hydrolysis products are formed when each wax...Ch. 19 - Prob. 39PCh. 19 - Prob. 40PCh. 19 - Draw a triacylglycerol that fits each description:...Ch. 19 - Draw a triacylglycerol that fits each description:...Ch. 19 - Draw the structure of a triacylglycerol that...Ch. 19 - Draw the structure of a triacylglycerol that...Ch. 19 - Consider the following four types of compounds:...Ch. 19 - How do fats and oils compare with respect to each...Ch. 19 - For the food product shown in the accompanying...Ch. 19 - For the food product shown in the accompanying...Ch. 19 - Answer the following questions about the given...Ch. 19 - Answer the following questions about the given...Ch. 19 - Draw the products formed when each triacylglycerol...Ch. 19 - Draw the products formed when each triacylglycerol...Ch. 19 - Which of the following are phospholipids: (a)...Ch. 19 - Prob. 54PCh. 19 - Prob. 55PCh. 19 - Prob. 56PCh. 19 - wIn transporting molecules or ions across a cell...Ch. 19 - Prob. 58PCh. 19 - Draw the structure of the anabolic steroid...Ch. 19 - Draw the structure of the anabolic steroid...Ch. 19 - Why must cholesterol be transported through the...Ch. 19 - Describe the role of HDLs and LDL5 in cholesterol...Ch. 19 - Prob. 63PCh. 19 - Prob. 64PCh. 19 - (a) Draw the structure of an estrogen and an...Ch. 19 - (a) Draw the structure of an androgen and a...Ch. 19 - What are the similarities and differences between...Ch. 19 - Why aren’t prostaglandins classified as hormones?Ch. 19 - What two structural features characterize all...Ch. 19 - List three biological functions of prostaglandins...Ch. 19 - Explain why aspirin and celecoxib differ in how...Ch. 19 - How does zileuton treat the cause of asthma, not...Ch. 19 - Answer each question with regard to vitamins A and...Ch. 19 - Answer each question in Problem 19.73 for vitamins...Ch. 19 - Give an example of each type of lipid. a. a...Ch. 19 - Give an example of each type of lipid. a. a...Ch. 19 - Consider each of the following components: [1]...Ch. 19 - Consider each of the following components: [1]...Ch. 19 - Block diagrams representing the general structures...Ch. 19 - For each block diagram in Problem 19.79, label the...Ch. 19 - Prob. 81PCh. 19 - Prob. 82PCh. 19 - Prob. 83PCh. 19 - Prob. 84PCh. 19 - Prob. 85PCh. 19 - Prob. 86PCh. 19 - Can an individual survive on a completely fat-free...Ch. 19 - Prob. 88PCh. 19 - Prob. 89PCh. 19 - Prob. 90PCh. 19 - Prob. 91PCh. 19 - Prob. 92PCh. 19 - Prob. 93CPCh. 19 - Prob. 94CP
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