Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 19, Problem 5P

Understanding the Action of Fluoroacetate on the TCA Cycle

In a tissue where the TCA cycle has been inhibited by fluoroacetate, what difference in the concentration of each TCA cycle metabolite would you expect, compared with a normal, uninhibited tissue?

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Considering the complete oxidation of an 18-C fatty acid. Give the answer to the following question.a.  What is the total number of NADH produced in TCA if all of the acetyl CoA enters the cycle? b. What is the total number of FADH2 produced in TCA if all the acetyl CoA enters the cycle?c. How much ATP is produced in the overall oxidation?
Considering the complete oxidation of an 18-C fatty acid. Give the answer for the following question.a. How many rounds of beta-oxidation is needed?b. How many NADH molecules are produced in beta-oxidation only?c. How many FADH2 molecules are produced in beta-oxidation only?d. How many Acetyl Co-A are produced?
Number of electrons generated for complex Il in oxidation of 2 acetyl CoA via the TCA Cycle.
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